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| == Contraindications == | | == Contraindications == |
| | #Hyperkalemia |
| | #Preexisting hyperkalemia |
| | #Burns >5d old |
| | #Crush injury >5d old |
| | #Severe infection >5d old |
| | #Neuromuscular diseases, myopathies |
| | #History of malignant hyperthermia |
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| {| style="width: 500px" border="1" cellpadding="1" cellspacing="1"
| | Note: in MG theoretically need increased dose |
| |-
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| | '''Contraindication<br/>'''
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| | '''From-To'''
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| |-
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| | Known hyperK
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| | current
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| |-
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| | Massive burns >10% BSA
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| | >4dys-healed
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| |-
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| | Massive crush injuries
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| | >4dys-healed
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| |-
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| | Denervation^
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| | >4dys-6mo
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| |-
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| | Neuromuscular dz^^
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| | indefinite
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| |-
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| | Intra-abdominal sepsis
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| | >5dys-resolution
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| |-
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| | Increased ICP
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| | may use w/ defacic dose
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| |}
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| ^CVA (in particular those with residual deficits), spinal cord injury
| | == Source == |
| | Tintinalli |
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| ^^ALS, MS, skeletal muscle myopathies, cholinesterase def, h/o malignant hyperthermia
| | Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis. |
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| *No evidence to support contraindication in penetrating eye injuries
| | [[Category:Drugs]] |
| *N.B. Myasthenia Gravis- theoretically need more succ to induce vs nondepolarizing agents which have a prolonged effect.
| | [[Category:Airway/Resus]] |
| *This is 2/2 to lack of post-synaptic receptors, i.e. succ cannot potentiate a reaction 2/2 too few receptors.
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| *Vs. it takes few "molecules" of roc/vec to block the few remaining functioning receptors.
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| *Overall, most practitioners tend to avoid succ in all patients with possible neuromuscular disease.
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| == Source ==
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| 2/06 DONALDSON (Adapted from Rosen)
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| | |
| Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis.<br/>
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| | |
| [[Category:Drugs]] <br/>[[Category:Airway/Resus]] | |
Contraindications
- Hyperkalemia
- Preexisting hyperkalemia
- Burns >5d old
- Crush injury >5d old
- Severe infection >5d old
- Neuromuscular diseases, myopathies
- History of malignant hyperthermia
Note: in MG theoretically need increased dose
Source
Tintinalli
Levitan, R. Annals of EM. Vol 45, Issue 2. Safety of succinylcholine in myasthenia gravis.
