Vitamin K deficiency: Difference between revisions
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=See Also= | =See Also= | ||
*[[Warfarin (Coumadin) Reversal]] | *[[Warfarin (Coumadin) Reversal]] | ||
*[[ | *[[Coagulopathy (Main)]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revision as of 13:56, 7 January 2014
Background
- Cofactor for vitamin K-dependent clotting factors II, VII, IX, X
- Used by liver
- Fat soluble
Differential Diagnosis of Deficiency
- Nutritional deficiency
- Malabsorption
- Cholestasis: since it is fat soluble and needs bile salts to be absorbed
Treatment for Deficiency
- Fresh Frozen Plasma: 1ml contains 1U of each clotting factor
- Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off
