Procedures in patients with coagulopathies: Difference between revisions

No edit summary
Line 1: Line 1:
==Paracentesis==
==Paracentesis==
no data supporting cutoff values for coags/platelets beyond which paracent should be avoided/prophylactically transfused
*no data supporting cutoff values for coags/platelets beyond which paracent should be avoided/prophylactically transfused
 
*routine use of FFP and platelets is not recommended
the routine use of fresh frozen plasma and platelet concentrates is not recommended
*contraindicated only if DIC or fibrinolysis
 
*incidence of clinically significant bleeding complications low even in liver failure (< 0.2%)
contraindicated only if DIC or fibrinolysis
*Greatly increased serum creatinine levels --> consider post-procedure observation
 
incidence of clinically significant bleeding complications low even in liver failure (< 0.2%)
 
Greatly increased serum creatinine levels --> consider post-procedure observation


==Thoracentesis==
==Thoracentesis==
Transfuse if plat <50,000, or PT/PTT twice nl range (Mcvay)
*Transfuse if plat <50,000, or PT/PTT twice nl range (Mcvay)


==Lumbar Puncture==
==Lumbar Puncture==
Tranfuse if plat <50,000, or PT/PTT > 1.5 times nl
*Tranfuse if plat <50,000, or PT/PTT > 1.5 times nl
 
*If hemophiliac, replace factor before LP
If hemophiliac, replace factor before LP


==Central Line==
==Central Line==
No benefit FFP if artery isn't hit (Am J Surg '01)
*No benefit FFP if artery isn't hit (Am J Surg '01)
 
*Consider transfuse if plat <50,000
Consider transfuse if plat <50,000
*Use compressible site if coagulopathic (jury is still out)
 
Use compressible site if coagulopathic (jury is still out)


==Sources==
==Sources==

Revision as of 23:22, 16 July 2012

Paracentesis

  • no data supporting cutoff values for coags/platelets beyond which paracent should be avoided/prophylactically transfused
  • routine use of FFP and platelets is not recommended
  • contraindicated only if DIC or fibrinolysis
  • incidence of clinically significant bleeding complications low even in liver failure (< 0.2%)
  • Greatly increased serum creatinine levels --> consider post-procedure observation

Thoracentesis

  • Transfuse if plat <50,000, or PT/PTT twice nl range (Mcvay)

Lumbar Puncture

  • Tranfuse if plat <50,000, or PT/PTT > 1.5 times nl
  • If hemophiliac, replace factor before LP

Central Line

  • No benefit FFP if artery isn't hit (Am J Surg '01)
  • Consider transfuse if plat <50,000
  • Use compressible site if coagulopathic (jury is still out)

Sources

Paracentesis: Kaji Questions, Thomsen TW. Paracentesis. N Engl J Med 2006; 355: e21.; Roberts, Clin Proc Emer Med 2004; Yu (Clin Liv Dz '01)

8/14/06 DONALDSON (adapted from Lampe, Charfen)