Vecuronium: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
*Not recommended for RSI | *Not recommended for [[RSI]] | ||
*0.15mg/kg IV based on ideal body weight, can prime with 0.01mg/kg IV | *0.15mg/kg IV based on ideal body weight, can prime with 0.01mg/kg IV | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Not recommended for RSI | *Not recommended for [[RSI]] | ||
==Special Populations== | ==Special Populations== | ||
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*Metabolism: Hepatic | *Metabolism: Hepatic | ||
*Excretion: Renal | *Excretion: Renal | ||
*Mechanism of Action: Non-depolarizing neuromuscular blocking agent. Long duration with slow onset. Competes for cholinergic receptors at the motor end-plate. Acetylcholinesterase inhibitors like those found in organophosphates antagonize this action | *Mechanism of Action: Non-depolarizing neuromuscular blocking agent. Long duration with slow onset. Competes for cholinergic receptors at the motor end-plate. [[Acetylcholinesterase inhibitors]] like those found in organophosphates antagonize this action | ||
==See Also== | ==See Also== | ||
*[[Critical care quick reference]] | *[[Critical care quick reference]] | ||
*Reversal agent: [[Sugammadex]] | |||
==References== | ==References== | ||
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<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:Critical Care]] | |||
Latest revision as of 23:26, 23 September 2019
General
- Type: Neuromuscular blocker, nondepolarizing, fast
- Dosage Forms: IV
- Common Trade Names: Norcuron
Adult Dosing
- Not recommended for RSI
- 0.15mg/kg IV based on ideal body weight, can prime with 0.01mg/kg IV
Pediatric Dosing
- Not recommended for RSI
Special Populations
- Pregnancy Rating: C
- Lactation: Infant risk cannot be ruled out
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: Varies, from 30-60 minutes
- Metabolism: Hepatic
- Excretion: Renal
- Mechanism of Action: Non-depolarizing neuromuscular blocking agent. Long duration with slow onset. Competes for cholinergic receptors at the motor end-plate. Acetylcholinesterase inhibitors like those found in organophosphates antagonize this action
See Also
- Critical care quick reference
- Reversal agent: Sugammadex
References
Micromedex