Anion Gap (Low): Difference between revisions

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==Background==
#REDIRECT[[Anion gap]]
 
 
< 7 meq/L
 
 
==DDX==
 
 
1) Lab error
 
2) Decreased "unmeasured" anions
 
    a) hypoalbuminemia*
 
3) Increased "unmeasured" cations
 
    a) hyperkalemia
 
    b) hypercalcemia
 
    c) hypermagnesemia
 
    d) lithium intoxication
 
4) increased cationic paraprotein
 
    a) multiple myeloma (do a serum protein electrophoresis to w/o)
 
    b) polyclonal IgG gammopathy.
 
5)  Pseudo
 
    a) severe hypernatremia (>170 meq/L)
 
          -true concentration of sodium is underestimated
 
    b) marked hyperlipidemia (marked overestimation of the plasma chloride concentration)
 
    c) bromide intoxication (e.g. for myasthenia gravis and some herbal medications)
 
*AG falls by about 2.5 meq/L for every 1 g/dL (10 g/L) reduction in the plasma albumin concentration
 
== ==
 
 
==Source==
 
 
Kaji Questions
 
 
 
 
 
[[Category:Tox]]

Latest revision as of 18:34, 14 May 2015

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