Terbutaline: Difference between revisions
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==General== | ==General== | ||
*Type: Beta 2 agonist | *Type: [[Beta 2 agonist]] | ||
*Dosage Forms: | *Dosage Forms: 1mg/mL injection | ||
==Adult Dosing== | ==Adult Dosing== | ||
===[[Preterm labor]]=== | ===[[Preterm labor]]=== | ||
*0.25mg sq q20-30 min up to 4 doses | *0.25mg sq q20-30 min, up to 4 doses PRN contractions | ||
===Asthma/Bronchoconstriction=== | ===Asthma/Bronchoconstriction=== | ||
*0.25mg sq q20 min up to 3 doses | *0.25mg sq q20 min, up to 3 doses | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===Asthma/Bronchoconstriction=== | |||
*0.005-0.01mg/kg to max 0.4mg SQ q15-20 min, up to 3 doses; may repeat in 2-6 hours | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: Category C | ||
*Lactation: | *Lactation: Not recommended | ||
*Renal Dosing | *Renal Dosing: n/a | ||
*Hepatic Dosing: n/a | |||
*Hepatic Dosing | |||
==Contraindications== | ==Contraindications== | ||
| Line 26: | Line 25: | ||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Black box warning against prolonged use for tocolysis (>48-72 hrs) | |||
*Cardiac arrhythmia | |||
===Common=== | ===Common=== | ||
*Agitation, tremor, hyperglycemia, hypokalemia | |||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Onset: 6-15 minutes | ||
*Metabolism: | *Half-life: 11-16 hours | ||
*Excretion: | *Metabolism: Hepatic | ||
*Mechanism of Action: | *Excretion: Urine | ||
*Mechanism of Action: Beta 2 agonist, smooth muscle relaxant | |||
==See Also== | ==See Also== | ||
[[Asthma]], [[Preterm Labor]] | |||
== | ==References== | ||
Lexicomp | |||
<references/> | <references/> | ||
[[Category: | [[Category:Pharmacology]] | ||
Latest revision as of 22:49, 23 September 2019
General
- Type: Beta 2 agonist
- Dosage Forms: 1mg/mL injection
Adult Dosing
Preterm labor
- 0.25mg sq q20-30 min, up to 4 doses PRN contractions
Asthma/Bronchoconstriction
- 0.25mg sq q20 min, up to 3 doses
Pediatric Dosing
Asthma/Bronchoconstriction
- 0.005-0.01mg/kg to max 0.4mg SQ q15-20 min, up to 3 doses; may repeat in 2-6 hours
Special Populations
- Pregnancy Rating: Category C
- Lactation: Not recommended
- Renal Dosing: n/a
- Hepatic Dosing: n/a
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Black box warning against prolonged use for tocolysis (>48-72 hrs)
- Cardiac arrhythmia
Common
- Agitation, tremor, hyperglycemia, hypokalemia
Pharmacology
- Onset: 6-15 minutes
- Half-life: 11-16 hours
- Metabolism: Hepatic
- Excretion: Urine
- Mechanism of Action: Beta 2 agonist, smooth muscle relaxant
See Also
References
Lexicomp