Template:Encephalitis Treatment: Difference between revisions

Latest revision as of 13:10, 20 March 2026

Often it is unclear which type of encephalitis is present and starting Acyclovir empirically is appropriate. In addition to the pathogens below, possible causes can include West Nile Virus, EBV, HIV, toxoplasmosis, or rabies.

HSV encephalitis

Acyclovir 10mg/kg (10-15mg/kg for pediatrics) every 8hrs

HZV encephalitis

Acyclovir 10mg/kg every 8hr

CMV encephalitis

Ganciclovir 5mg/kg IV every 12hr OR
Foscarnet 90mg/kg IV every 12 hrs

Tick Associated (Borrelia burgdorferi, Ehrlichiosis or Rickettsia)

Doxycycline 200 mg IV once followed by 100 mg IV twice daily

Pediatric

HSV Encephalitis

Acyclovir 20mg/kg IV q8hrs x 21 days (neonates); 10-15mg/kg IV q8hrs x 14-21 days (children)

CMV Encephalitis

Ganciclovir 5mg/kg IV q12hrs

Tick Associated

Doxycycline 2.2mg/kg IV q12hrs (max 100mg/dose)

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 ''Often it is unclear which type of encephalitis is present and starting [[Acyclovir]] empirically is appropriate. In addition to the pathogens below, possible causes can include [[West Nile Virus]], [[EBV]], [[HIV]], [[toxoplasmosis]], or [[rabies]].
 ===[[HSV]] encephalitis===
-*[[Acyclovir]] 10mg/kg (10-15mg/kg for pediatrics) every 8hrs
+*{{AntibioticDose|disease=Encephalitis|drug=Acyclovir|dose=10mg/kg (10-15mg/kg for pediatrics) every 8hrs|context=HSV}}
 ===[[HZV]] encephalitis===
 *[[Acyclovir]] 10mg/kg every 8hr
 ===[[CMV]] encephalitis===
-*[[Ganciclovir]] 5mg/kg IV every 12hr OR
+*{{AntibioticDose|disease=Encephalitis|drug=Ganciclovir|dose=5mg/kg IV every 12hr|context=CMV}} OR
-*[[Foscarnet]] 90mg/kg IV every 12 hrs
+*{{AntibioticDose|disease=Encephalitis|drug=Foscarnet|dose=90mg/kg IV every 12 hrs|context=CMV}}
+===Tick Associated ([[Borrelia burgdorferi]], [[Ehrlichiosis]] or [[Rickettsia]])===
+*{{AntibioticDose|disease=Encephalitis|drug=Doxycycline|dose=200 mg IV once followed by 100 mg IV twice daily|context=Tick Associated}}
-===Tick Associated ([[Borrelia burgdorferi]], [[Ehrlichiosis]] or [[Rickettsia]])===
+===Pediatric===
-*[[Doxycycline]] 200 mg IV once followed by 100 mg IV twice daily
+====HSV Encephalitis====
+*{{AntibioticDose|disease=Encephalitis|drug=Acyclovir|dose=20mg/kg IV q8hrs x 21 days (neonates); 10-15mg/kg IV q8hrs x 14-21 days (children)|context=Pediatric HSV|population=Pediatric}}
+====CMV Encephalitis====
+*{{AntibioticDose|disease=Encephalitis|drug=Ganciclovir|dose=5mg/kg IV q12hrs|context=Pediatric CMV|population=Pediatric}}
+====Tick Associated====
+*{{AntibioticDose|disease=Encephalitis|drug=Doxycycline|dose=2.2mg/kg IV q12hrs (max 100mg/dose)|context=Pediatric Tick Associated|population=Pediatric}}