Template:Babesiosis Antibiotics: Difference between revisions

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(Fix formatting: add bullet to Option 1, remove stray Clindamycin link from Option 2)
 
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''Each regimin is for 10 days duration and option 1 is often used for mild parasitemia <4% with option two for sever cases with >4% parasite load''
''Each regimen is for 10 days duration and option 1 is often used for mild parasitemia <4% with option two for severe cases with >4% parasite load''
 
===Option 1===
===Option 1===
*Atovaquone (750mg BID) and [[Azithromycin]] (500-1000mg on first day, 250-1000mg on subsequent days)<ref>Krause PJ, Lepore T, Sikand VK, Gadbaw J Jr, Burke G, Telford SR 3rd, et al. Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med. Nov 16 2000;343(20):1454-8.</ref>
*{{AntibioticDose|disease=Babesiosis|drug=Atovaquone|dose=750mg BID x 10 days|context=Mild parasitemia less than 4 percent option 1|population=Adult}} and {{AntibioticDose|disease=Babesiosis|drug=Azithromycin|dose=500-1000mg day 1 then 250-1000mg daily x 10 days|context=Mild parasitemia less than 4 percent option 1 with Atovaquone|population=Adult}}<ref>Krause PJ, Lepore T, Sikand VK, Gadbaw J Jr, Burke G, Telford SR 3rd, et al. Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med. Nov 16 2000;343(20):1454-8.</ref>


===Option 2===
===Option 2===
[[Clindamycin]]
{{Babesiosis Clindamycin Adult}}
{{Babesiosis Clindamycin Adult}}


===Pediatrics===
===Pediatrics===
*[[Clindamycin]] 20mg/kg/day for children and 25mg/kg/day for children for 7-10 days
*{{AntibioticDose|disease=Babesiosis|drug=Clindamycin|dose=20-40mg/kg/day PO divided TID x 7-10 days (max 600mg/dose)|context=Pediatric, with Quinine|population=Pediatric}}
*{{AntibioticDose|disease=Babesiosis|drug=Quinine|dose=8mg/kg PO q8h x 7-10 days (Max: 648mg/dose)|context=Severe parasitemia with Clindamycin|population=Pediatric}}

Latest revision as of 14:03, 20 March 2026

Each regimen is for 10 days duration and option 1 is often used for mild parasitemia <4% with option two for severe cases with >4% parasite load

Option 1

Option 2

  • Clindamycin 600mg PO q8hrs x 7-10 days (or 300-600mg IV q6hrs)
  • Give with Quinine 650mg TID

Pediatrics

  • Clindamycin 20-40mg/kg/day PO divided TID x 7-10 days (max 600mg/dose)
  • Quinine 8mg/kg PO q8h x 7-10 days (Max: 648mg/dose)
  1. Krause PJ, Lepore T, Sikand VK, Gadbaw J Jr, Burke G, Telford SR 3rd, et al. Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med. Nov 16 2000;343(20):1454-8.