Template:Diagnosis of SBP: Difference between revisions

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====Standard Evaluation====
====Standard Evaluation====
*Paracentesis results supporting a diagnosis of SBP:
*Paracentesis results supporting a diagnosis of SBP:
**Absolute neutrophil count (PMNs) ≥250
**Absolute neutrophil count (PMNs) ≥250, pH <7.35, OR blood-ascites pH gradient >0.1<ref>Wilkerson R, Sinert, R. The Use of Paracentesis in the Assessment of the Patient With Ascites. Ann Emerg Med 2009, 54(3): 465-68.</ref>
**Bacteria on [[gram stain]] (single type)
**Bacteria on [[gram stain]] (single type)
**SAAG > 1.1
**SAAG > 1.1
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''For bloody tap, subtract 1 WBC for every 250 RBC<ref>Hoefs JC "Increase in ascites white blood cell and protein concentrations during diuresis in patients with chronic liver disease."Hepatology. 1981;1(3):249. PMID 7286905</ref>
''For bloody tap, subtract 1 WBC for every 250 RBC<ref>Hoefs JC "Increase in ascites white blood cell and protein concentrations during diuresis in patients with chronic liver disease."Hepatology. 1981;1(3):249. PMID 7286905</ref>


====If on Peritoneal Dialysis (CAPD)====
====If on peritoneal dialysis====
[[SBP]] if:
''See  [[Peritoneal dialysis-associated peritonitis]]''
*>100 total WBCs OR >50% neutrophils
*Cell count >100/mm with >50% neutrophils most consistent with infection<ref>ISPD GUIDELINES/RECOMMENDATIONS http://www.ispd.org/guidelines/articles/update/ispdperitonitis.pdf</ref>
 
====If on Nightly APD====
[[SBP]] if:
* >50% neutrophils
* Amylase (>100 suggestive of intra-abdominal process)

Latest revision as of 16:24, 26 June 2018

Diagnosis of SBP via Ascitic Fluid Analysis

Standard Evaluation

  • Paracentesis results supporting a diagnosis of SBP:
    • Absolute neutrophil count (PMNs) ≥250, pH <7.35, OR blood-ascites pH gradient >0.1[1]
    • Bacteria on gram stain (single type)
    • SAAG > 1.1
      • Diagnostic of portal hypertension with 97% accuracy[2]
      • SBP rarely develops in patients without portal hypertension
    • Protein < 1, Glucose > 50 (otherwise concern for secondary bacterial peritonitis)

For bloody tap, subtract 1 WBC for every 250 RBC[3]

If on peritoneal dialysis

See Peritoneal dialysis-associated peritonitis

  • Cell count >100/mm with >50% neutrophils most consistent with infection[4]
  1. Wilkerson R, Sinert, R. The Use of Paracentesis in the Assessment of the Patient With Ascites. Ann Emerg Med 2009, 54(3): 465-68.
  2. Runyon BA, Montano AA, Akriviadis EA, et al. The serum-ascites albumin gradient is superior to the exudate-transudate concept in the differential diagnosis of ascites. Ann Intern Med 1992; 117:215.
  3. Hoefs JC "Increase in ascites white blood cell and protein concentrations during diuresis in patients with chronic liver disease."Hepatology. 1981;1(3):249. PMID 7286905
  4. ISPD GUIDELINES/RECOMMENDATIONS http://www.ispd.org/guidelines/articles/update/ispdperitonitis.pdf