Bleeding treatments: Difference between revisions

Latest revision as of 15:30, 27 January 2022

Treatments

References

Authors:

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 ==Treatments==
+#[[Packed_red_blood_cells|Packed Red Blood Cells]]
+#[[DDAVP]] 0.3mg/kg subQ or IV (max 20mg)
+#[[Platelet transfusion|Platelets]]
+#[[Fresh frozen plasma|FFP]]
+#[[Cryoprecipitate]]
+#[[Vitamin_K|Vitamin K (10mg SQ/IM)]]
+#[[Unfractionated_heparin_reversal|Protamine (Heparin reversal)]]
+#Estrogen (Uterine, renal)
+#[[PPI]]/[[famotidine]]/[[octreotide]] ([[GI bleed|GI]])
+#[[Quick_Clot_(Kaolin)|Quick Clot (Topical)]]
+#[[TXA]]
+==See Also==
+*[[Coagulopathy (Main)]]
+*[[Hemorrhage]]
+*[[Blood products]]
+*[[Massive transfusion]]
-) PRBCs
+==References==
+<references/>
-) DDAVP (0.3mirog/kq SQ/IV)
-) Platelets
-) FFP
-) Cryopreticipate
-) Vitamin K (10mg SQ/IM)
-) Protamine (Heparin)
-) Estrogen (Renal)
-) PPI/Pepcid/Octreotide (GI)
-==Warfarin/Vitamin K Def==
-(inc PT/INR)
--FFP
--Vitamin K (+/- takes 24hrs to affect & 2wk to wear off)
-==Heparin/Lovenox==
-(inc PTT)
--Protamie (1mg IV Q100 U of heparin in previous 4hrs)
--Massive bleed --> cryoprecipitate (10 U IV), then FFP (& platelets, aminocaproic acid infusion if nec)
-==Liver Disease==
--Vitamin K
--PPI/pepcid/octreotide (variceal bleed)
--FFP (& platlets if low)
--DDAVP
-==Renal Disease==
--PRBCs (<8 Hb)
--Hemodialysis
--DDAVP
--Conjugated estrogens (unknown mechanism)
--*Cyroprecipitate & platelets (in life-threatening bleed only)
-==DIC==
-(see also DIC)
--IVF
--PRBCs
--Vitamin K
--Folate (1mg IV)
-If bleeding predominant DIC:
--FFP (2 U at a time)
--Cryoprecipitate (10 bags at a time)
-(Heparin is contraversial in thrombosis predominant DIC)
-==Factor VIII Inhibitor==
-(PTT does not correct after mixing)
--high dose Factor VII, prothrombin, or recombinant factor VIIa
-==Lupus Anticoagulant==
-(rare)
--warfarin or ASA
-==Source ==
-/22/06 DONALDSON (adapted from Tintinalli's)
 [[Category:Heme/Onc]]