Blood products

Background

Types

• Packed red blood cells
• Platelet transfusion
• Fresh frozen plasma
• Cryoprecipitate transfusion
• Humate-P
• Prothrombin complex concentrates

Transfusion Risk Ratios

Rate	Complication
1:10	Febrile non-hemolytic transfusion reaction per pool of 5 donor units of platelets (1 pack)
1:100	Minor allergic reactions (urticaria)
1:300	Febrile non-hemolytic transfusion reaction per unit of RBC (1 pack)
1:700	Transfusion-associated circulatory overload per transfusion episode
1:5,000	Transfusion-related acute lung injury (TRALI)
1:7,000	Delayed hemolytic transfusion reaction
1:10,000	Symptomatic bacterial sepsis per pool of 5 donor units of platelets
1:40,000	Death from bacterial sepsis per pool of 5 donor units of platelets
1:40,000	ABO-incompatible transfusion per RBC transfusion episode
1:40,000	Serious allergic reaction per unit of component
1:82,000	Transmission of hepatitis B virus per unit of component
1:100,000	Symptomatic bacterial sepsis per unit of RBC
1:500,000	Death from bacterial sepsis per unit of RBC
1:1,000,000	Transmission of West Nile Virus
1:3,000,000	Transmission of HTLV per unit of component
1:3,100,000	Transmission of hepatitis C virus per unit of component
1:4,700,000	Transmission of HIV per unit of component

See Also

• Transfusions
• Acute transfusion reaction
• Extravascular hemolytic tranfusion reaction
• Graft-vs-host disease
• Transfusion-associated graft-versus-host disease
• Massive Transfusion Protocol
• Coagulopathy (Main)
• TXA