Adenovirus: Difference between revisions
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==Evaluation== | ==Evaluation== | ||
*Typically clinical diagnosis after excluding other possible treatable infection | |||
*Antigen detection, PCR assay, virus isolation, and serology can be used to identify adenovirus infections, but the presence of virus does not necessarily mean it is associated with disease | |||
==Management== | ==Management== | ||
Revision as of 17:39, 10 August 2016
Background
- Medium-sized (90-100 nm), non-enveloped icosohedral viruses with double-stranded DNA
- > 50 types of adenoviruses can cause infections in humans
- Relatively resistant to common disinfectants and environmental conditions
Clinical Features
- Adenoviruses affect many different organ systems.
- Most commonly respiratory ill
- Common cold, pneumonia, croup, and bronchitis
- Gastroenteritis
- Conjunctivitis
- Cystitis
- Less commonly central nervous system involvement
- Most commonly respiratory ill
- More severe infection in immunocompromised individuals
- Transmitted primarily via respiratory droplets, but also by fecal routes
Differential Diagnosis
Evaluation
- Typically clinical diagnosis after excluding other possible treatable infection
- Antigen detection, PCR assay, virus isolation, and serology can be used to identify adenovirus infections, but the presence of virus does not necessarily mean it is associated with disease