Meniere's disease: Difference between revisions

(Text replacement - "r/o" to "rule out")
(Text replacement - " prednisone" to " prednisone")
Line 35: Line 35:
**Acetazolamide
**Acetazolamide
**Avoid loop diuretics due to ototoxicity
**Avoid loop diuretics due to ototoxicity
*Consider IM steroid injection, followed by tapered PO prednisone<ref>Sajjadi H. Medical management of Meniere's disease. Otolaryngol Clin North Am. 2002 Jun. 35(3):581-9, vii.</ref>
*Consider IM steroid injection, followed by tapered PO [[prednisone]]<ref>Sajjadi H. Medical management of Meniere's disease. Otolaryngol Clin North Am. 2002 Jun. 35(3):581-9, vii.</ref>
*Routine ENT referral for medical treatment failures (endolymphatic decompression, vestibular nerve section, labyrunthectomy, intra-TM injections)<ref>Pullens B, Giard JL, Verschuur HP, van Benthem PP. Surgery for Ménière's disease. Cochrane Database Syst Rev. 2010 Jan 20. CD005395.</ref><ref>Barrs DM. Intratympanic corticosteroids for Meniere's disease and vertigo. Otolaryngol Clin North Am. 2004 Oct. 37(5):955-72, v.</ref>
*Routine ENT referral for medical treatment failures (endolymphatic decompression, vestibular nerve section, labyrunthectomy, intra-TM injections)<ref>Pullens B, Giard JL, Verschuur HP, van Benthem PP. Surgery for Ménière's disease. Cochrane Database Syst Rev. 2010 Jan 20. CD005395.</ref><ref>Barrs DM. Intratympanic corticosteroids for Meniere's disease and vertigo. Otolaryngol Clin North Am. 2004 Oct. 37(5):955-72, v.</ref>



Revision as of 09:09, 3 August 2016

Background

  • Occurs due to increased endolymph within the cochlea and labyrinth
  • First attack usually occurs in patients >65yrs
  • Usually is unilateral but may become bilateral with time

Clinical Features

  • Episodes of sudden-onset vertigo with nausea/vomiting
    • Duration: usually 2-8hr
    • Frequency: Ranges from several episodes per week to several times per month
  • Roaring tinnitus
  • Diminished hearing
  • Fullness in affected ear
  • Between attacks patient is well (although decreased hearing may persist)

Differential Diagnosis

Vertigo

Evaluation

Management

  • Treat vertigo symptomatically with scopolamine, antihistamines, or benzodiazepines
  • Vestibulosuppressant options[2]
    • Meclizine 25-50mg PO
    • Diazepam 5-10mg PO or IV
    • Other options: scopolamine, promethazine, prochlorperazine, metoclopramide
  • Diuretics may decrease fluid pressure in ear:
    • HCTZ
    • Acetazolamide
    • Avoid loop diuretics due to ototoxicity
  • Consider IM steroid injection, followed by tapered PO prednisone[3]
  • Routine ENT referral for medical treatment failures (endolymphatic decompression, vestibular nerve section, labyrunthectomy, intra-TM injections)[4][5]

Disposition

  • Refer to ENT

References

  1. Lorenzi MC, Bento RF, Daniel MM, Leite CC. Magnetic resonance imaging of the temporal bone in patients with Ménière's disease. Acta Otolaryngol. 2000 Aug. 120(5):615-9.
  2. Minor LB, Schessel DA, Carey JP. Ménière's disease. Curr Opin Neurol. 2004 Feb. 17(1):9-16.
  3. Sajjadi H. Medical management of Meniere's disease. Otolaryngol Clin North Am. 2002 Jun. 35(3):581-9, vii.
  4. Pullens B, Giard JL, Verschuur HP, van Benthem PP. Surgery for Ménière's disease. Cochrane Database Syst Rev. 2010 Jan 20. CD005395.
  5. Barrs DM. Intratympanic corticosteroids for Meniere's disease and vertigo. Otolaryngol Clin North Am. 2004 Oct. 37(5):955-72, v.