ACTH (cosyntropin) stimulation test: Difference between revisions

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Cosyntropin
Cosyntropin  
#Before: Draw serum cortisol
#Time 0: ^0.25mg IM/IV over 2min
#Time 30: Draw serum cortisol
#Time 60: Draw serum cortisol & give 100mg hydrodortison IVP
^0.125mg if <2yrs old


Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
#Before: Draw serum cortisol
Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
#Time 0: ^0.25mg IM/IV over 2min
#Time 30: Draw serum cortisol
#Time 60: Draw serum cortisol &amp; give 100mg hydrodortison IVP


==Treatment==
^0.125mg if &lt;2yrs old
#Then give either
 
##dexamethasone 6mg IV
Normal Response: Cortisol level doubles from baseline after Cosyntropin administration
##OR
 
Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration
 
== Treatment ==
 
#Then give either  
##dexamethasone 6mg IV  
##OR  
##Hydrocortisone 100mg IV
##Hydrocortisone 100mg IV


==Source ==
== Source ==
2/22/06 DONALDSON (from Pharmacopoeia)
 
Emedicine Adrenal Crisis in Emergency Medicine
2/22/06 DONALDSON (from Pharmacopoeia)  
 
Emedicine: Adrenal Crisis in Emergency Medicine  


[[Category:Endo]]
[[Category:Endo]]

Revision as of 08:54, 28 February 2012

Cosyntropin

  1. Before: Draw serum cortisol
  2. Time 0: ^0.25mg IM/IV over 2min
  3. Time 30: Draw serum cortisol
  4. Time 60: Draw serum cortisol & give 100mg hydrodortison IVP

^0.125mg if <2yrs old

Normal Response: Cortisol level doubles from baseline after Cosyntropin administration

Adrenal Insufficiency: Cortisol level fails to rise after Cosyntropin administration

Treatment

  1. Then give either
    1. dexamethasone 6mg IV
    2. OR
    3. Hydrocortisone 100mg IV

Source

2/22/06 DONALDSON (from Pharmacopoeia)

Emedicine: Adrenal Crisis in Emergency Medicine