Nitroprusside: Difference between revisions
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Sodium nitroprusside is primarily used as a potent vasodilator. It works predominantly in arterioles and venules as a result of its breakdown to nitric oxide (NO).<ref>"nitroprusside sodium (Rx) - Nipride, Nitropress, more..". Medscape Reference. WebMD. Retrieved 20 November 2013.</ref> It is intravenously infused in cases of acute hypertensive crises and its effect is usually seen within minutes. Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload. | Sodium nitroprusside is primarily used as a potent vasodilator. It works predominantly in arterioles and venules as a result of its breakdown to nitric oxide (NO).<ref>"nitroprusside sodium (Rx) - Nipride, Nitropress, more..". Medscape Reference. WebMD. Retrieved 20 November 2013.</ref> It is intravenously infused in cases of acute hypertensive crises and its effect is usually seen within minutes. Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload. | ||
== Adult Dosing== | ==Adult Dosing== | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
== Contraindications== | ==Contraindications== | ||
== Indications== | ==Indications== | ||
== Mechanism of Action== | ==Mechanism of Action== | ||
Potent arteriolar dilation from its active metabolite, nitric oxide (NO). | Potent arteriolar dilation from its active metabolite, nitric oxide (NO). | ||
== Adverse Drug Reactions== | ==Adverse Drug Reactions== | ||
*[[Cyanide|Cyanide toxicity]] | *[[Cyanide|Cyanide toxicity]] | ||
== Kinetics== | ==Kinetics== | ||
==See Also== | ==See Also== | ||
Revision as of 14:39, 6 July 2016
Background
Sodium nitroprusside is primarily used as a potent vasodilator. It works predominantly in arterioles and venules as a result of its breakdown to nitric oxide (NO).[1] It is intravenously infused in cases of acute hypertensive crises and its effect is usually seen within minutes. Nitric oxide reduces both total peripheral resistance and venous return, thus decreasing both preload and afterload.
Adult Dosing
Pediatric Dosing
Contraindications
Indications
Mechanism of Action
Potent arteriolar dilation from its active metabolite, nitric oxide (NO).
Adverse Drug Reactions
Kinetics
See Also
- ↑ "nitroprusside sodium (Rx) - Nipride, Nitropress, more..". Medscape Reference. WebMD. Retrieved 20 November 2013.