Alport syndrome: Difference between revisions
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==Clinical Features== | ==Clinical Features== | ||
The degree of clinical features are related to the severity of the organ systems involved. Most common patient will have: | |||
*Lower extremity [[edema]] due to the [[hyoalbuimemia]] | |||
*[[Hematuria]] | |||
*[[Hypertension]] | |||
*[[Hearing Loss]] | |||
*Visual problems | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 05:38, 28 June 2016
Background
A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to ESRD. Most genetic in the COL4A5 gene and are inherited in an X-linked pattern.[1]
Clinical Features
The degree of clinical features are related to the severity of the organ systems involved. Most common patient will have:
- Lower extremity edema due to the hyoalbuimemia
- Hematuria
- Hypertension
- Hearing Loss
- Visual problems
Differential Diagnosis
Diagnosis
Management
Disposition
See Also
External Links
References
- ↑ Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.