Opioid toxicity: Difference between revisions
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# | ==Background== | ||
*Obtain acetaminophin levels in all cases of combination opioid-acetaminophen overdoses | |||
*Respiratory depression is the cause of all mortality from opioid toxicity | |||
==Clinical Features== | |||
*Miosis | |||
*N/V | |||
*Respiratory depression | |||
*Mental status depression | |||
==DDX== | |||
#Clonidine toxicity | |||
#Organophosphate toxicity | |||
#Sedative-hypnotic toxicity | |||
#CO poisoning | |||
#Hypoglycemia | |||
#Postictal state | |||
#CVA | |||
==Treatment== | |||
Narcan (initial Dose 0.4 to 2mg) | |||
Caution in chronic users, who are otherwise hemodynamically stable | |||
Narcan gtt started at 2/3 the dose first required to awaken the patient per hour | |||
==Diagnosis== | |||
==Source== | |||
*Tintinalli | |||
[[Category:Tox]] | |||
Revision as of 02:20, 5 January 2012
Background
- Obtain acetaminophin levels in all cases of combination opioid-acetaminophen overdoses
- Respiratory depression is the cause of all mortality from opioid toxicity
Clinical Features
- Miosis
- N/V
- Respiratory depression
- Mental status depression
DDX
- Clonidine toxicity
- Organophosphate toxicity
- Sedative-hypnotic toxicity
- CO poisoning
- Hypoglycemia
- Postictal state
- CVA
Treatment
Narcan (initial Dose 0.4 to 2mg)
Caution in chronic users, who are otherwise hemodynamically stable
Narcan gtt started at 2/3 the dose first required to awaken the patient per hour
Diagnosis
Source
- Tintinalli