Digoxin: Difference between revisions

 
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#REDIRECT [[Digoxin Toxicity]]
== Adult Dosing ==
*Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg
 
== Contraindications ==
*WPW
**Increases conduction velocity in atrial tissue
 
== Indications ==
*RVR control in a-fib/flutter, PSVT
 
== Mechanism of Action ==
*Inhibits NaK pump
**Positive inotropy
*Negative chronotropy/dromotropy
**Indirect vagal stimulator
 
== Adverse Drug Rxns ==
*GI - N/V, diarrhea, abd pain
*CV - Bradycardia, SA/AV block, ventr arrhythmias
 
== Kinetics ==
Onset of action = 1.5-4hr (IV)
 
==See Also==
*[[Digoxin Toxicity]]
*[[Antiarrhythmics]]
 
[[Category:Drugs]]

Revision as of 21:50, 18 November 2011

Adult Dosing

  • Loading dose = 0.25 mg IV q2hr until effect (max total = 1.5 mg

Contraindications

  • WPW
    • Increases conduction velocity in atrial tissue

Indications

  • RVR control in a-fib/flutter, PSVT

Mechanism of Action

  • Inhibits NaK pump
    • Positive inotropy
  • Negative chronotropy/dromotropy
    • Indirect vagal stimulator

Adverse Drug Rxns

  • GI - N/V, diarrhea, abd pain
  • CV - Bradycardia, SA/AV block, ventr arrhythmias

Kinetics

Onset of action = 1.5-4hr (IV)

See Also