Mycophenolate mofetil: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===Kidney transplant rejection prophylaxis=== | |||
*1 g PO/IV bid | |||
*Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach; stable pts may take w/ food | |||
===Heart transplant rejection prophylaxis=== | |||
*1.5 g PO/IV bid | |||
*Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach | |||
===Liver transplant rejection prophylaxis=== | |||
*1.5 g PO bid or 1 g IV bid | |||
*Info: start IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach | |||
===Lupus nephritis=== | |||
*1 g PO bid | |||
*Info: use w/ prednisone, consider decease dose 50% after 6mo tx | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 22:32, 10 February 2016
Administration
- Type: Immunosuppressant
- Dosage Forms: 250,500; 200 mg/mL; IV
- Routes of Administration: PO, IV
- Common Trade Names: CellCept
Adult Dosing
Kidney transplant rejection prophylaxis
- 1 g PO/IV bid
- Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach; stable pts may take w/ food
Heart transplant rejection prophylaxis
- 1.5 g PO/IV bid
- Start: IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach
Liver transplant rejection prophylaxis
- 1.5 g PO bid or 1 g IV bid
- Info: start IV w/ in 24h post transplant, continue up to 14 days, switch to PO ASAP; Info: give on empty stomach
Lupus nephritis
- 1 g PO bid
- Info: use w/ prednisone, consider decease dose 50% after 6mo tx
Pediatric Dosing
Special Populations
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: