Respiratory alkalosis: Difference between revisions

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==Background==
==Background==
*alkalemia = pH >7.42
*respiratory alkalosis = pCO2 <38
*Cause = hyperventilation
*Cause = hyperventilation
*May lead to hypocalcemia, hypokalemia
*May lead to hypocalcemia, hypokalemia
*Check for a concurrent acid/base disturbance
**always check for an AG
**for every 10mm pCO2 <40, HCO3 expected to decrease by 1-3.5 mEq
**if HCO3 < 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a superimposed primary metabolic acidosis
**if HCO3 > 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a primary metabolic alkalosis, or acute respiratory alkalosis without time for metabolic compensation


==DDX==
==DDX==
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#Anxiety
#Anxiety
#Hypoxia
#Hypoxia
#Fever
#early sepsis/fever/pneumonia
#Hyperthyroid
#Hyperthyroid
#Sympathomimetics
#Sympathomimetics
#[[Aspirin (Salicylate) Toxicity]]
#[[Aspirin (Salicylate) Toxicity]]
#Progesterone
#Progesterone/pregnancy
#Liver dz
#Liver dz
#CVA or other central cause


==Source ==
==Source ==
Tintinalli
KAJI 2011
Tintinalli, Kaji 2011


[[Category:FEN]]
[[Category:FEN]]
[[Category:Pulm]]
[[Category:Pulm]]
[[Category:Tox]]

Revision as of 20:30, 2 August 2011

Background

  • alkalemia = pH >7.42
  • respiratory alkalosis = pCO2 <38
  • Cause = hyperventilation
  • May lead to hypocalcemia, hypokalemia
  • Check for a concurrent acid/base disturbance
    • always check for an AG
    • for every 10mm pCO2 <40, HCO3 expected to decrease by 1-3.5 mEq
    • if HCO3 < 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a superimposed primary metabolic acidosis
    • if HCO3 > 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a primary metabolic alkalosis, or acute respiratory alkalosis without time for metabolic compensation

DDX

  1. Asthma
  2. PE
  3. DKA
  4. Anxiety
  5. Hypoxia
  6. early sepsis/fever/pneumonia
  7. Hyperthyroid
  8. Sympathomimetics
  9. Aspirin (Salicylate) Toxicity
  10. Progesterone/pregnancy
  11. Liver dz
  12. CVA or other central cause

Source

KAJI 2011 Tintinalli, Kaji 2011