Respiratory alkalosis: Difference between revisions
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==Background== | ==Background== | ||
*alkalemia = pH >7.42 | |||
*respiratory alkalosis = pCO2 <38 | |||
*Cause = hyperventilation | *Cause = hyperventilation | ||
*May lead to hypocalcemia, hypokalemia | *May lead to hypocalcemia, hypokalemia | ||
*Check for a concurrent acid/base disturbance | |||
**always check for an AG | |||
**for every 10mm pCO2 <40, HCO3 expected to decrease by 1-3.5 mEq | |||
**if HCO3 < 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a superimposed primary metabolic acidosis | |||
**if HCO3 > 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a primary metabolic alkalosis, or acute respiratory alkalosis without time for metabolic compensation | |||
==DDX== | ==DDX== | ||
| Line 9: | Line 16: | ||
#Anxiety | #Anxiety | ||
#Hypoxia | #Hypoxia | ||
# | #early sepsis/fever/pneumonia | ||
#Hyperthyroid | #Hyperthyroid | ||
#Sympathomimetics | #Sympathomimetics | ||
#[[Aspirin (Salicylate) Toxicity]] | #[[Aspirin (Salicylate) Toxicity]] | ||
#Progesterone | #Progesterone/pregnancy | ||
#Liver dz | #Liver dz | ||
#CVA or other central cause | |||
==Source == | ==Source == | ||
Tintinalli | KAJI 2011 | ||
Tintinalli, Kaji 2011 | |||
[[Category:FEN]] | [[Category:FEN]] | ||
[[Category:Pulm]] | [[Category:Pulm]] | ||
[[Category:Tox]] | |||
Revision as of 20:30, 2 August 2011
Background
- alkalemia = pH >7.42
- respiratory alkalosis = pCO2 <38
- Cause = hyperventilation
- May lead to hypocalcemia, hypokalemia
- Check for a concurrent acid/base disturbance
- always check for an AG
- for every 10mm pCO2 <40, HCO3 expected to decrease by 1-3.5 mEq
- if HCO3 < 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a superimposed primary metabolic acidosis
- if HCO3 > 24 - (40-pCO2)/10 x 2.5 (+/-1) then there is a primary metabolic alkalosis, or acute respiratory alkalosis without time for metabolic compensation
DDX
- Asthma
- PE
- DKA
- Anxiety
- Hypoxia
- early sepsis/fever/pneumonia
- Hyperthyroid
- Sympathomimetics
- Aspirin (Salicylate) Toxicity
- Progesterone/pregnancy
- Liver dz
- CVA or other central cause
Source
KAJI 2011 Tintinalli, Kaji 2011
