Ascending cholangitis: Difference between revisions
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# | ===Diagnosis=== | ||
# Charcot's Triad: Fever + jaundice + RUQ pain | |||
## Occurs in 50-75% | |||
# Reynold's Pentad: The triad + AMS + hypotension | |||
## Hypotension may be the only presenting sign in elderly pts | |||
# Labs | |||
## Leukocytosis with neutrophil predominance | |||
## Elevated alk phos, conj. bilirubin | |||
## Blood culture is indicated | |||
# Imaging | |||
## [[Ultrasound: Gallbladder|RUQ Ultrasound]] | |||
### Dilatation of CBD ( > 6mm) and presence of choledocholithiasis | |||
### May miss small CBD stones and in acute cases CBD may not have had time to dilate | |||
# ERCP | |||
## Should be obtained to confirm the diagnosis and to intervene | |||
===Treatment=== | |||
# Broad-spectrum parenteral Abx covering gram - and anerobes | |||
## CTX + metronidazole OR piperacillin/tazobactam (Zosyn) OR ampicillin-sulbactam (Unasyn) | |||
==See Also== | |||
[[Gallbladder Disease (Main)]] | |||
[[Category:GI]] | |||
[[Category:ID]] | |||
Revision as of 21:38, 18 July 2011
Diagnosis
- Charcot's Triad: Fever + jaundice + RUQ pain
- Occurs in 50-75%
- Reynold's Pentad: The triad + AMS + hypotension
- Hypotension may be the only presenting sign in elderly pts
- Labs
- Leukocytosis with neutrophil predominance
- Elevated alk phos, conj. bilirubin
- Blood culture is indicated
- Imaging
- RUQ Ultrasound
- Dilatation of CBD ( > 6mm) and presence of choledocholithiasis
- May miss small CBD stones and in acute cases CBD may not have had time to dilate
- RUQ Ultrasound
- ERCP
- Should be obtained to confirm the diagnosis and to intervene
Treatment
- Broad-spectrum parenteral Abx covering gram - and anerobes
- CTX + metronidazole OR piperacillin/tazobactam (Zosyn) OR ampicillin-sulbactam (Unasyn)
