Lung abscess: Difference between revisions

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==Background==
==Background==
*Localized, suppurative necrotizing process occurring w/in the pulmonary parenchyma
*Localized, suppurative necrotizing process occurring within the pulmonary parenchyma
*Takes 7-14d for aspiration PNA to develop into an abscess
*Microbiology
*Microbiology
**Community-acquired: [[anaerobes]] (bacteroides, fusobacterium)
**Community-acquired: [[anaerobes]] (bacteroides, fusobacterium)
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===Causes===
===Causes===
*Aspiration [[PNA]]
*Aspiration [[PNA]] (7-14 days to become lung abscess)
*Bacteremia from nonpulmonary infection
*Bacteremia from nonpulmonary infection
*Pulmonary infarction
*Pulmonary infarction
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==Clinical Presentation==
==Clinical Presentation==
*Several weeks of cough, fever, pleuritic chest pain, wt loss, night sweats
*Cough, fever, pleuritic chest pain, wt loss, night sweats (generally over course of several weeks)
**Tachycardia, tachypnea, or fever may be absent
**Tachycardia, tachypnea, or fever may be absent


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*Loop of bowel extending through diaphragmatic hernia
*Loop of bowel extending through diaphragmatic hernia


==Diagnosis==
==Diagnostic Evaluation==
*CXR
*CXR or CT Chest
*Dense consolidation w/ air-fluid level inside of a thick-walled cavitary lesion
*Dense consolidation w/ air-fluid level inside of a thick-walled cavitary lesion
**Air-fluid level indicates communicatio nof abscess cavity w/ a bronchiole
**Air-fluid level indicates communication of abscess cavity with a bronchiole


==Treatment==
==Management==
*Medical management will successfully treat 70-90% of lung abscesses
*Medical management will successfully treat 70-90% of lung abscesses
**Drainage occurs spontaneously from communication of cavity w/ tracheobronchial tree
**Drainage occurs spontaneously from communication of cavity w/ tracheobronchial tree
**Bronchoscopic drainage may result in seeding other parts of the lung
**Bronchoscopic drainage may result in seeding other parts of the lung
*[[Antibiotics]]
*Antibiotics
**[[Clindamycin]] + 2nd or 3rd gen [[cephalosporin]] OR
**[[Clindamycin]] + 2nd or 3rd gen [[cephalosporin]] '''OR'''
**[[Clindamycin]] + [[ampicillin/sulbactam]]
**[[Clindamycin]] + [[ampicillin/sulbactam]]


==Complications==
==Complications==
*Empyema
*Empyema
*Massive Hemoptysis
*Massive hemoptysis
*Failure of cavity to resolve


==Disposition==
==Disposition==
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*[[Empyema]]
*[[Empyema]]


==Source==
==References==
Tintinalli
<References/>


[[Category:ID]]
[[Category:ID]]
[[Category:Pulm]]
[[Category:Pulm]]

Revision as of 09:17, 6 September 2015

Background

Causes

  • Aspiration PNA (7-14 days to become lung abscess)
  • Bacteremia from nonpulmonary infection
  • Pulmonary infarction
  • Infection as a result of penetrating chest trauma
  • Primary and metastatic neoplasms
  • Wegener's, sarcoidosis

Clinical Presentation

  • Cough, fever, pleuritic chest pain, wt loss, night sweats (generally over course of several weeks)
    • Tachycardia, tachypnea, or fever may be absent

Differential Diagnosis

  • Cavitary lesion w/ air-fluid level
  • Infected bullae
  • Pleural fluid collection with bronchopleural fistula
  • Loop of bowel extending through diaphragmatic hernia

Diagnostic Evaluation

  • CXR or CT Chest
  • Dense consolidation w/ air-fluid level inside of a thick-walled cavitary lesion
    • Air-fluid level indicates communication of abscess cavity with a bronchiole

Management

  • Medical management will successfully treat 70-90% of lung abscesses
    • Drainage occurs spontaneously from communication of cavity w/ tracheobronchial tree
    • Bronchoscopic drainage may result in seeding other parts of the lung
  • Antibiotics

Complications

  • Empyema
  • Massive hemoptysis

Disposition

  • Admit

See Also

References