Hydrocortisone topical: Difference between revisions
| Line 2: | Line 2: | ||
*Type: [[Topical steroid]] | *Type: [[Topical steroid]] | ||
*Dosage Forms: 0.5%, 1%, 2.5% crm, lotion, oint | *Dosage Forms: 0.5%, 1%, 2.5% crm, lotion, oint | ||
*Common Trade Names: | *Common Trade Names: Cortizone, Cortaid, Hytone, Texacort | ||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 21:10, 26 June 2015
General
- Type: Topical steroid
- Dosage Forms: 0.5%, 1%, 2.5% crm, lotion, oint
- Common Trade Names: Cortizone, Cortaid, Hytone, Texacort
Adult Dosing
dermatoses, steroid-responsive: apply bid-qid
Pediatric Dosing
dermatoses, steroid-responsive: apply bid-qid
Special Populations
- Pregnancy Rating: C
- Lactation: Probably safe
- Renal Dosing
- Adult: none
- Pediatric: none
- Hepatic Dosing
- Adult: none
- Pediatric: none
Contraindications
- Allergy to class/drug
- caution if skin infection
- caution in pediatric pts
Adverse Reactions
Serious
- HPA axis suppresion
- Cushing syndrome
- hyperglycemia
- intracranial HTN (peds pts)
Common
- burning
- pruritus
- irritation
- dryness
- folliculitis
- hypertrichosis
- acneiform dermatitis
- hypopigmentation
- perioral dermatitis
- allergic contact dermatitis
- maceration
- secondary infection
- skin atrophy
- striae
- miliaria
Pharmacology
- Half-life: 8-12h
- Metabolism: liver primarily; CYP450
- Excretion: urine
- Mechanism of Action: exact mechanim of anti-inflammatory action unknown; inhibits multiple inflammatory cytokines; produces multiple gluocorticoid and mineralocorticoid effects