Anemia of spaceflight: Difference between revisions
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==Background== | ==Background== | ||
The anemia of space flight (1% Hb loss per day)<ref>Leach CS, Johnson PC. Influence of spaceflight on erythrokinetics in man. Science. 1984;225(4658):216-218.</ref><ref>Udden MM, Driscoll TB, Pickett MH, Leach-Huntoon CS, Alfrey CP. Decreased production of red blood cells in human subjects exposed to microgravity. J Lab Clin Med. 1995;125(4):442-449.</ref><ref>Alfrey CP, Udden MM, Leach-Huntoon C, Driscoll T, Pickett MH. Control of red blood cell mass in spaceflight. J Appl Physiol. 1996; 81(1):98-104.</ref> It was first described in relation to the Gemini astronauts<ref> Fischer CL, Johnson PC, Berry CA. Red blood cell mass and plasma volume changes in manned space flight. JAMA. 1967;200(7): 579-583.</ref> | The anemia of space flight (1% Hb loss per day)<ref>Leach CS, Johnson PC. Influence of spaceflight on erythrokinetics in man. Science. 1984;225(4658):216-218.</ref><ref>Udden MM, Driscoll TB, Pickett MH, Leach-Huntoon CS, Alfrey CP. Decreased production of red blood cells in human subjects exposed to microgravity. J Lab Clin Med. 1995;125(4):442-449.</ref><ref>Alfrey CP, Udden MM, Leach-Huntoon C, Driscoll T, Pickett MH. Control of red blood cell mass in spaceflight. J Appl Physiol. 1996; 81(1):98-104.</ref> It was first described in relation to the Gemini astronauts.<ref> Fischer CL, Johnson PC, Berry CA. Red blood cell mass and plasma volume changes in manned space flight. JAMA. 1967;200(7): 579-583.</ref> | ||
==Clinical Features== | ==Clinical Features== | ||
Revision as of 21:40, 29 April 2024
Background
The anemia of space flight (1% Hb loss per day)[1][2][3] It was first described in relation to the Gemini astronauts.[4]
Clinical Features
Differential Diagnosis
Anemia
RBC Loss
RBC consumption (Destruction/hemolytic)
- Hereditary
- Acquired
- Microangiopathic Hemolytic Anemia (MAHA)
- Autoimmune hemolytic anemia
Impaired Production (Hypochromic/microcytic)
- Iron deficiency
- Anemia of chronic disease
- Thalassemia
- Sideroblastic anemia
Aplastic/myelodysplastic (normocytic)
Megaloblastic (macrocytic)
- Vitamin B12/folate deficiency
- Drugs (chemo)
- HIV
Evaluation
Workup
Diagnosis
Management
Disposition
See Also
External Links
References
- ↑ Leach CS, Johnson PC. Influence of spaceflight on erythrokinetics in man. Science. 1984;225(4658):216-218.
- ↑ Udden MM, Driscoll TB, Pickett MH, Leach-Huntoon CS, Alfrey CP. Decreased production of red blood cells in human subjects exposed to microgravity. J Lab Clin Med. 1995;125(4):442-449.
- ↑ Alfrey CP, Udden MM, Leach-Huntoon C, Driscoll T, Pickett MH. Control of red blood cell mass in spaceflight. J Appl Physiol. 1996; 81(1):98-104.
- ↑ Fischer CL, Johnson PC, Berry CA. Red blood cell mass and plasma volume changes in manned space flight. JAMA. 1967;200(7): 579-583.