Template:Pediatric anticonvulsants: Difference between revisions
(Created page with "===Pediatric Anticonvulsants Table === {| class="wikitable" ! Drug !! Dose !! Infusion Rate (Minutes)!! Age !! Comments/Cautions |- | Levetiracetam || *60 mg/kg/dose IV/IO *MAX: 3000 mg/dose || ≥5 || Any || Most commonly used agent |- | Fosphenytoin || *20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM *MAX: 1000 PE/dose || ≥10 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR |- | Valproic acid || *40 mg/kg/dose IV/IO...") |
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| [[Levetiracetam]] || | | [[Levetiracetam]] || | ||
*60 mg/kg/dose IV/IO | *60 mg/kg/dose IV/IO | ||
*MAX: | *MAX: 4500 mg/dose | ||
|| ≥5 || Any || Most commonly used agent | || ≥5 || Any || Most commonly used agent | ||
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*20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM | *20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM | ||
*MAX: 1000 PE/dose | *MAX: 1000 PE/dose | ||
|| ≥10 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | || ≥10 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures | ||
|- | |- | ||
| [[Valproic acid]] || | | [[Valproic acid]] || | ||
| Line 21: | Line 21: | ||
*20 mg/kg/dose IV/IO | *20 mg/kg/dose IV/IO | ||
*MAX: 1000 mg/dose | *MAX: 1000 mg/dose | ||
|| ≥20 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR | || ≥20 || Any || Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures | ||
|- | |- | ||
| [[Phenobarbital]] || | | [[Phenobarbital]] || | ||
*20 mg/kg/dose IV/IO | *20 mg/kg/dose IV/IO | ||
*MAX: 1000 mg/dose | *MAX: 1000 mg/dose | ||
|| ≥20 || <6 months || Respiratory depression, especially in combination with | || ≥20 || <6 months || First line for most neonatal seizures. Respiratory depression, especially in combination with benzodiazepines | ||
|} | |} | ||
Latest revision as of 16:14, 28 October 2023
Pediatric Anticonvulsants Table
| Drug | Dose | Infusion Rate (Minutes) | Age | Comments/Cautions |
|---|---|---|---|---|
| Levetiracetam |
|
≥5 | Any | Most commonly used agent |
| Fosphenytoin |
|
≥10 | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures |
| Valproic acid |
|
≥10 | ≥2 years | Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay |
| Phenytoin |
|
≥20 | Any | Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures |
| Phenobarbital |
|
≥20 | <6 months | First line for most neonatal seizures. Respiratory depression, especially in combination with benzodiazepines |