Lisinopril: Difference between revisions
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*Common Trade Names: Prinivil, Zestril | *Common Trade Names: Prinivil, Zestril | ||
General information: | General information: | ||
* Doses > 40 mg/day rarely more effective | |||
* Decreased efficacy as mono therapy in african-american patients | |||
* Obtain Chem 10 if starting in ED to assess renal function | |||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 02:22, 1 April 2015
General
- Type: ACE inhibitor
- Dosage Forms: 2.5, 5, 10, 20, 30, 40
- Common Trade Names: Prinivil, Zestril
General information:
- Doses > 40 mg/day rarely more effective
- Decreased efficacy as mono therapy in african-american patients
- Obtain Chem 10 if starting in ED to assess renal function
Adult Dosing
- HTN: 10 - 40 mg PO Qday, max 80 mg/day
Pediatric Dosing
- 6-16 year old: 0.07 mg/kg PO qday, max 40 mg/day
Special Populations
- Pregnancy Rating: D
- Lactation: Safety unknown
- Renal Dosing
- Adult: CrCl < 30, start 2.5 mg qday, max 40 mg q/day
- Pediatric Cr Cl 30-50: decrease dose 50%, CrCl < 30, avoid use
- Hepatic Dosing
- Adult: Not defined
- Pediatric: Not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: