Ibuprofen: Difference between revisions
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**Contraindicated for treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery | **Contraindicated for treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery | ||
*Gastrointestinal risk | *Gastrointestinal risk | ||
** | **Increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal | ||
***Elderly patients are at greater risk for serious GI events. | ***Elderly patients are at greater risk for serious GI events. | ||
Revision as of 03:46, 28 March 2015
General
- Type: NSAID
- Dosage Forms:
- Common Trade Names: Advil; Motrin
Adult Dosing
- 600mg PO Q6hours
Pediatric Dosing
- 10 mg/kg PO Q6hours
- Max: 40 mg/kg/day
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
- Cardiovascular
- May cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal
- Contraindicated for treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
- Gastrointestinal risk
- Increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal
- Elderly patients are at greater risk for serious GI events.
- Increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal
Adverse Reactions
Serious
- GI bleeding
- ulceration and perforation of the stomach or intestines
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: