Glucagon: Difference between revisions
(/* Beta-blocker toxicityKerns W. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007;25(2):309-331. (Review) Bailey B (2003). Glucagon in beta-blocker and calcium channel blocker overdoses: a sys...) |
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| Line 11: | Line 11: | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===[[Beta-blocker toxicity]] <ref name="KernsEMC" />=== | ===[[Beta-blocker toxicity]] <ref name="KernsEMC" /> <ref name="BaileyCT" />=== | ||
*Ped: 50mcg/kg | *Ped: 50mcg/kg | ||
*Rebolus if no response after 10min | *Rebolus if no response after 10min | ||
Revision as of 18:26, 8 March 2015
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Beta-blocker toxicity[1] [2]
- 5mg IV bolus over one minute
- Rebolus if no response after 10min
- If effective, start infusion at 2-5mg/hr
Pediatric Dosing
Beta-blocker toxicity [1] [2]
- Ped: 50mcg/kg
- Rebolus if no response after 10min
- If effective, start infusion at 70mcg/kg/hr
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life: 20 minutes
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- ↑ 1.0 1.1 Kerns W. Management of beta-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007;25(2):309-331. (Review)
- ↑ 2.0 2.1 Bailey B (2003). Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review. Journal of toxicology. Clinical toxicology, 41 (5), 595-602 PMID: 14514004
- Consider concurrent administration of ondansetron (causes n/v)
- Rebolus if no response after 10min
- Effects persist for 10-15 min
- If effective start infusion at:
- Adult: 2-5mg/hr
- Ped: 70mcg/kg/hr