Etomidate: Difference between revisions
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''See [[critical care quick reference]] for drug doses by weight.'' | ''See [[critical care quick reference]] for drug doses by weight.'' | ||
==General== | ==General== | ||
*Type: | *Type: | ||
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===Controversy=== | ===Controversy=== | ||
"The available evidence suggests that etomidate suppresses adrenal function transiently without | "The available evidence suggests that etomidate suppresses adrenal function transiently without | ||
demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality." | demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."<ref>*Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.</ref> | ||
==Pharmacology== | ==Pharmacology== | ||
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==Sources== | ==Sources== | ||
<references/> | |||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 03:05, 24 February 2015
See critical care quick reference for drug doses by weight.
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
RSI
- 0.3 mg/kg bolus IV
- Standard dose = 20mg
Procedural Sedation
- 0.15 mg/kg bolus IV
- Standard dose = 10mg)
Pediatric Dosing
See critical care quick reference for drug doses by weight.
RSI
- 0.3 mg/kg bolus IV
- Max: 20mg
Procedural Sedation
- (0.15 mg/kg bolus IV
- Max: 10mg
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Controversy
"The available evidence suggests that etomidate suppresses adrenal function transiently without demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."[1]
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Sources
- ↑ *Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.