Anavip: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
*Administer as soon as possible following North American Pit Viper bite with signs of envenomation. | *Administer as soon as possible following North American Pit Viper bite with signs of envenomation. | ||
===Initial Loading Dose=== | |||
*May repeat with an additional 10-vial dose every hour as needed | *10 vials IV | ||
*May repeat with an additional 10-vial dose every hour as needed until local signs of envenomation are not progressing, systemic symptoms are resolved, and coagulation and other laboratory parameters have normalized or are trending toward normal. | |||
===Maintenance Therapy=== | |||
*4 vials IV PRN for any reemerging symptoms | |||
*There is no known maximum dose. | *There is no known maximum dose. | ||
===Administration=== | |||
*IV: Infuse IV over 60 minutes. Infuse at a rate of 25 to 50 mL/hour for the first 10 minutes, carefully monitoring for any allergic reactions. If no reactions occur, increase the infusion rate incrementally to 250 mL/hour until completion. | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 19:48, 2 August 2021
Administration
- Crotaline (Pit Vipers) equine immune F(ab')2 antivenom
- Type: Antivenom
- Routes of Administration: IV
- Common Trade Names: Anavip
Adult Dosing
- Administer as soon as possible following North American Pit Viper bite with signs of envenomation.
Initial Loading Dose
- 10 vials IV
- May repeat with an additional 10-vial dose every hour as needed until local signs of envenomation are not progressing, systemic symptoms are resolved, and coagulation and other laboratory parameters have normalized or are trending toward normal.
Maintenance Therapy
- 4 vials IV PRN for any reemerging symptoms
- There is no known maximum dose.
Administration
- IV: Infuse IV over 60 minutes. Infuse at a rate of 25 to 50 mL/hour for the first 10 minutes, carefully monitoring for any allergic reactions. If no reactions occur, increase the infusion rate incrementally to 250 mL/hour until completion.
Pediatric Dosing
Special Populations
Pregnancy Rating
Lactation risk
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion: