Zollinger-Ellison syndrome: Difference between revisions
Farmersj333 (talk | contribs) (Created page with "==Background== *aka S-E syndrome *gastric neuroendocrine malignancy results in hypersecretion of hydrochloric acid by parietal cells ==Clinical Features== *Hematemesis *Chron...") |
No edit summary |
||
| Line 2: | Line 2: | ||
*aka S-E syndrome | *aka S-E syndrome | ||
*gastric neuroendocrine malignancy results in hypersecretion of hydrochloric acid by parietal cells | *gastric neuroendocrine malignancy results in hypersecretion of hydrochloric acid by parietal cells | ||
*Associated with peptic ulcers and diarrhea | |||
*60% malignant, only 20% resectable; 25% of gastrinoma patients have multiple endocrine neoplasia type I; >80% of gastrinomas found in gastrinoma triangle. | |||
==Clinical Features== | ==Clinical Features== | ||
Revision as of 20:50, 27 February 2021
Background
- aka S-E syndrome
- gastric neuroendocrine malignancy results in hypersecretion of hydrochloric acid by parietal cells
- Associated with peptic ulcers and diarrhea
- 60% malignant, only 20% resectable; 25% of gastrinoma patients have multiple endocrine neoplasia type I; >80% of gastrinomas found in gastrinoma triangle.
Clinical Features
- Hematemesis
- Chronic diarrhea
- Postprandial abdominal pain
- Nausea
- Wheezes on auscultation
- Evidence of malnourishment and decreased oral intake