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| ==Fever==
| | *[[Fever in traveler]] |
| # get incubation period- if > 1mo, dengue, rickettsia, viral hem fvr less likely
| | *[[Eosinophilic fever]] |
| # cbc c diff, thick smear, lft, ua, blood/ stool cx, cxr, serologies for specific viruses
| | *[[Traveler's diarrhea]] |
| | *[[Travel skin conditions]] |
| | *[[Parasitic diseases]] |
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| ===Malaria===
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| # most imp cause of fvr
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| # plasmodium falciparum can be rapidly fatal and needs to be ruled out soon
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| # p falciparum from sub Saharan Africa, 90% of pt have sx within 1 mo of return
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| # p vivax- Asia and Latin, 50% pt have sx within 1 mo- 2% up to 1 yr out
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| # chemoprophylaxsis does not guarantee protection
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| # usually have fvr, but 10- 40% may not
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| # fvr q 48- 72 hr pathognomic of vivax, ovale, malariae infc
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| # can also have ha, cough, gi sx
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| # check thick smear initially and if neg, repeat in 12- 24 hrs
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| # thrombocytopenia and splenomegaly common
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| # p falciparum unpredictable- admit and monitor for hypoglycemia
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| # iv meds if renal, resp failure, ams, sx, shock, anemia, p falcip rbc load >4% in nonimmune pt
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| ===Dengue===
| | '''External Links''' |
| #aedes mosquito in urban area
| | * [https://wwwnc.cdc.gov/travel Center for Disease Control and Prevention - Travelers' Health] |
| # incubate for 4- 7d, influenza like prodrome, fvr, ha, myalgia, LN, rash
| | * [https://wwwnc.cdc.gov/travel/notices Center for Disease Control and Prevention - Travel Health Notices] |
| # dengue shock syndrome and hem fvr rare in travelers- usually in pt c prev infc
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| # leukopenia, thrombocytopenia
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| # dx by 4x increase in acute/ conv titres
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| ===Rickettsia/ Typhus===
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| # fvr, ha, myalgia
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| # xmitted by arthropods/ ticks
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| # painless eschar at inoculation site imp clue
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| # camping, hiking in grassy/ scrub area
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| # regional LN, rash, leukopenia, thrombocytopenia
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| # dx clinically
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| # tx c tetracycline
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| # confirm serologically
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| ===Leptospirosis===
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| # fvr, myalgia, ha, rash
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| # conjuntival suffusion characteristic but not common
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| # exp to fresh water while rafting, kayaking
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| # biphasic illness with meningitis, uveitis, transminitis, proteinuria, hematuria
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| # tx c pcn or tetra
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| # confirm by serology
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| ===Typhoid Fever===
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| # fvr, ha
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| # visiting friends in India, Phillipines Latin
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| # abd pain, constipation, -diarrhea rare
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| # leukopenia, thrombocytopenia, dry cough, LN
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| # insidious onset unlike dengue or rickettsia
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| # dx by blood cx for salmonella enterica serotype typhi
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| # serology unreliable
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| # tx empirically with flouroquinolone or 3rd gen cephal
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| # vaccine partially effecive and breakthrough infc possible
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| ===Hemorrhagic Fever===
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| # meningococcemia, malaria, leptospirosis, rickettsia- all treatable with abx
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| # also untreatable viruses- dengue, yellow fvr- but hem forms rarely seen in travelers
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| # also consider Ebola and Lassa fever- public health hazard
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| # h/o visit to rural area or contact with ill people in endemic area
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| # usually 3 wk after exposure
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| ==CNS Changes and Fever==
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| # malaria, tb, typhoid fvr, rickettsia, poliomyelitis, rabies, viral (Japanese/ West Nile/ tick borne) encephalitis
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| # meningococcal meningitis assoc with Haj to Mecca
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| # eosinophilic meningitis assoc c coccidiomycosis or angiostrongyliasis- rat lung worm to brain
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| # trypanosomiasis by tsetse fly- Africal sleeping sickness- red chancre at site of fly bite, fvr, ha, myalgia going to meningoencephalitis. May see trypansosomes in smear in acute phase
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| ==Resp Sx and Fever==
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| # consider strep pneumonia, influenza, mycoplasma, legionella, tb
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| # Q Fever- coxiella burnetti- fvr, pna, hepatitis and animal exposure
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| # Lofflers syn- pulm infiltrates, eosinophilia from transient migration of larval helminthes through lungs
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| # Cough also seen in malaria, typhoid fvr, scrub typhus, dengue
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| ==Sex/ Blood Exposure and Fever==
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| # can have fvr without genital findings- hiv, syphilis (treponema pallidum) cmv, ebv, hep B
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| # also from tattoo, piercing, share razor, blood xfsn
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| ==Eosinophilic Fever==
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| # >400 per cubic mm
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| # due to blood CA or allergy or helminthic infc
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| # hookworm, ascariasis, strongyloides, schistosomiasis, filariasis, visceral larva migrans, trichinosis, cocci
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| # eval with stool for O&P
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| # serology
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| # blood smear
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| # skin snips for microfilariae
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| ==Diarrhea==
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| # most respond to antibiotics or antimotility agents
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| # as duration of diarrhea increases, higher chance of parasitic cause
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| # giardia, cryptosporidiosis, entamoeba, cyclospora
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| # dysentery if stool bloody, fvr or wbc in stool- invasive inflamm enteropathy
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| # has abrupt onset, metastatic lesions, reactive arthopathies, or campylobacter assoc guillain barre- maybe flouroquinolone resis esp in SE Asia
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| # amoebic dysentery insidious and can get amoebic liver abscess
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| # if do not find infc cause of dysentery, eval pt for IBD or CA
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| # prolonged diarrhea and malabsorption- giardia or tropical sprue- does not respond to removal of gluten from diet- tx with tetra and folate
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| # also consider postinfectious disaccharidase deficiency or irritable bowel dz
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| # if diarrhea starts >1 mo after travel- not caused by travel
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| # tx regular travelers diarrhea with fluids, antimotility agents, abx- fluoro or macrolide
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| # tx invasive enteropathy- bloody/ fvr- same but no antimotility agents
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| # if bloody stool but no fvr, consider enterhemorrhagic E coli- do not give abx since will get hemolytic uremic syndrome in kids
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| #examine stool if diarrhea invasive, persistent, unresponsive to standard tx or immune compromised
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| # if persistent diarrhea, give empiric flouro or macrolide or consid metronidazole for giardia- most common parasite
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| # try lactose free diet
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| # chronic diarrhea usually self limited within 1 yr
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| ==Skin Conditions==
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| ===Papules===
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| # insect bites- cluster or linear distribution
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| # scabies- if sex active or backpacker
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| # seabathers eruption- confined to skin covered by swim suit- jellyfish larvae trapped under cloth
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| # cercarial dermatitis- skin exposed to freshwater schistosomes or coastal water clam diggers itch
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| ===Sub Q Swelling and Nodules===
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| # myasis- skin invaded by fly larvae- like boil but with central opening in which larvae may hide
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| # tungiasis
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| # loa loa
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| # trypanosomiasis
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| ===Ulcers===
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| # pyoderma/ ecthyma- secondary staph cellulitits post bite
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| # leishmaniasis
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| # mycobacterium marinum
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| ===Linear and Migratory Lesions===
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| # cutaneous larvae migrans- by soil contact with dog/ cat feces
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| # photodermatitis
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| ==Source==
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| Mistry
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| [[Category:ID]] | | [[Category:ID]] |
| | [[Category:Tropical Medicine]] |