Travel medicine: Difference between revisions

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==Fever==
*[[Fever in traveler]]
# get incubation period- if > 1mo, dengue, rickettsia, viral hem fvr less likely
*[[Eosinophilic fever]]
# cbc c diff, thick smear, lft, ua, blood/ stool cx, cxr, serologies for specific viruses
*[[Traveler's diarrhea]]
*[[Travel skin conditions]]
*[[Parasitic diseases]]


===Malaria===
# most imp cause of fvr
# plasmodium falciparum can be rapidly fatal and needs to be ruled out soon
# p falciparum from sub Saharan Africa, 90% of pt have sx within 1 mo of return
# p vivax- Asia and Latin, 50% pt have sx within 1 mo- 2% up to 1 yr out
# chemoprophylaxsis does not guarantee protection
# usually have fvr, but 10- 40% may not
# fvr q 48- 72 hr pathognomic of vivax, ovale, malariae infc
# can also have ha, cough, gi sx
# check thick smear initially and if neg, repeat in 12- 24 hrs
# thrombocytopenia and splenomegaly common
# p falciparum unpredictable- admit and monitor for hypoglycemia
# iv meds if renal, resp failure, ams, sx, shock, anemia, p falcip rbc load >4% in nonimmune pt


===Dengue===
'''External Links'''
#aedes mosquito in urban area
* [https://wwwnc.cdc.gov/travel Center for Disease Control and Prevention - Travelers' Health]
# incubate for 4- 7d, influenza like prodrome, fvr, ha, myalgia, LN, rash
* [https://wwwnc.cdc.gov/travel/notices Center for Disease Control and Prevention - Travel Health Notices]
# dengue shock syndrome and hem fvr rare in travelers- usually in pt c prev infc
# leukopenia, thrombocytopenia
# dx by 4x increase in acute/ conv titres
 
===Rickettsia/ Typhus===
# fvr, ha, myalgia
# xmitted by arthropods/ ticks
# painless eschar at inoculation site imp clue
# camping, hiking in grassy/ scrub area
# regional LN, rash, leukopenia, thrombocytopenia
# dx clinically
# tx c tetracycline
# confirm serologically
 
===Leptospirosis===
# fvr, myalgia, ha, rash
# conjuntival suffusion characteristic but not common
# exp to fresh water while rafting, kayaking
# biphasic illness with meningitis, uveitis, transminitis, proteinuria, hematuria
# tx c pcn or tetra
# confirm by serology
 
===Typhoid Fever===
# fvr, ha
# visiting friends in India, Phillipines Latin
# abd pain, constipation, -diarrhea rare
# leukopenia, thrombocytopenia, dry cough, LN
# insidious onset unlike dengue or rickettsia
# dx by blood cx for salmonella enterica serotype typhi
# serology unreliable
# tx empirically with flouroquinolone or 3rd gen cephal
# vaccine partially effecive and breakthrough infc possible
 
===Hemorrhagic Fever===
# meningococcemia, malaria, leptospirosis, rickettsia- all treatable with abx
# also untreatable viruses- dengue, yellow fvr- but hem forms rarely seen in travelers
# also consider Ebola and Lassa fever- public health hazard
# h/o visit to rural area or contact with ill people in endemic area
# usually 3 wk after exposure
 
==CNS Changes and Fever==
# malaria, tb, typhoid fvr, rickettsia, poliomyelitis, rabies, viral (Japanese/ West Nile/ tick borne) encephalitis
# meningococcal meningitis assoc with Haj to Mecca
# eosinophilic meningitis assoc c coccidiomycosis or angiostrongyliasis- rat lung worm to brain
# trypanosomiasis by tsetse fly- Africal sleeping sickness- red chancre at site of fly bite, fvr, ha, myalgia going to meningoencephalitis. May see trypansosomes in smear in acute phase
 
==Resp Sx and Fever==
# consider strep pneumonia, influenza, mycoplasma, legionella, tb
# Q Fever- coxiella burnetti- fvr, pna, hepatitis and animal exposure
# Lofflers syn- pulm infiltrates, eosinophilia from transient migration of larval helminthes through lungs
# Cough also seen in malaria, typhoid fvr, scrub typhus, dengue
 
==Sex/ Blood Exposure and Fever==
# can have fvr without genital findings- hiv, syphilis (treponema pallidum) cmv, ebv, hep B
# also from tattoo, piercing, share razor, blood xfsn
 
==Eosinophilic Fever==
# >400 per cubic mm
# due to blood CA or allergy or helminthic infc
# hookworm, ascariasis, strongyloides, schistosomiasis, filariasis, visceral larva migrans, trichinosis, cocci
# eval with stool for O&P
# serology
# blood smear
# skin snips for microfilariae
 
==Diarrhea==
# most respond to antibiotics or antimotility agents
# as duration of diarrhea increases, higher chance of parasitic cause
# giardia, cryptosporidiosis, entamoeba, cyclospora
# dysentery if stool bloody, fvr or wbc in stool- invasive inflamm enteropathy
# has abrupt onset, metastatic lesions, reactive arthopathies, or campylobacter assoc guillain barre- maybe flouroquinolone resis esp in SE Asia
# amoebic dysentery insidious and can get amoebic liver abscess
# if do not find infc cause of dysentery, eval pt for IBD or CA
# prolonged diarrhea and malabsorption- giardia or tropical sprue- does not respond to removal of gluten from diet- tx with tetra and folate
# also consider postinfectious disaccharidase deficiency or irritable bowel dz
# if diarrhea starts >1 mo after travel- not caused by travel
# tx regular travelers diarrhea with fluids, antimotility agents, abx- fluoro or macrolide
# tx invasive enteropathy- bloody/ fvr- same but no antimotility agents
# if bloody stool but no fvr, consider enterhemorrhagic E coli- do not give abx since will get hemolytic uremic syndrome in kids
#examine stool if diarrhea invasive, persistent, unresponsive to standard tx or immune compromised
# if persistent diarrhea, give empiric flouro or macrolide or consid metronidazole for giardia- most common parasite
# try lactose free diet
# chronic diarrhea usually self limited within 1 yr
 
==Skin Conditions==
===Papules===
# insect bites- cluster or linear distribution
# scabies- if sex active or backpacker
# seabathers eruption- confined to skin covered by swim suit- jellyfish larvae trapped under cloth
# cercarial dermatitis- skin exposed to freshwater schistosomes or coastal water clam diggers itch
 
===Sub Q Swelling and Nodules===
# myasis- skin invaded by fly larvae- like boil but with central opening in which larvae may hide
# tungiasis
# loa loa
# trypanosomiasis
 
===Ulcers===
# pyoderma/ ecthyma- secondary staph cellulitits post bite
# leishmaniasis
# mycobacterium marinum
 
===Linear and Migratory Lesions===
# cutaneous larvae migrans- by soil contact with dog/ cat feces
# photodermatitis
 
==Source==
Mistry


[[Category:ID]]
[[Category:ID]]
[[Category:Tropical Medicine]]

Latest revision as of 16:24, 13 January 2021