Vasopressin: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===Dosing=== | |||
*0.04 units/min | |||
===Rate of Titration=== | |||
*Fixed dose (do not titrate) | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
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==Adverse Reactions== | ==Adverse Reactions== | ||
*Bradycardia | |||
*Limb ischemia | |||
*Myocardial ischemia | |||
*Splanchnic ischemia | |||
==Pharmacology== | ==Pharmacology== | ||
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*Excretion: | *Excretion: | ||
*Mechanism of Action: | *Mechanism of Action: | ||
===Primary Receptor=== | |||
*V1 | |||
===Relative Effects=== | |||
*↑SVR | |||
*↓HR | |||
==Notes== | |||
*Adverse effects are dose-dependent | |||
*Acts on V1 receptors leading to ↑vasoconstriction and | |||
↑sensitivity to catecholamines in pts with shock | |||
===Indication=== | |||
*Adjunct for septic shock | |||
==See Also== | ==See Also== | ||
Revision as of 14:27, 20 December 2014
General
- Type: Vasopressors
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Dosing
- 0.04 units/min
Rate of Titration
- Fixed dose (do not titrate)
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
- Bradycardia
- Limb ischemia
- Myocardial ischemia
- Splanchnic ischemia
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Primary Receptor
- V1
Relative Effects
- ↑SVR
- ↓HR
Notes
- Adverse effects are dose-dependent
- Acts on V1 receptors leading to ↑vasoconstriction and
↑sensitivity to catecholamines in pts with shock
Indication
- Adjunct for septic shock