Erythema multiforme: Difference between revisions
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==Background== | ==Background== | ||
[[File:EM_picture.jpeg|thumb|Erythema Multiforme]] | [[File:EM_picture.jpeg|thumb|Erythema Multiforme]] | ||
*Erythema Multiforme (EM) is an acute, self-limited skin condition precipitated by a variety of factors: | |||
**Infections: | |||
***Viral: HSV, hepatitis, influenza A | |||
***Fungal: dermatophytosis, histoplasmosis, coccidioidomycosis | |||
***Bacterial: streptococcus, tuberculosis | |||
**Drugs: | |||
***Antibiotics (penicillin, sulfonamides), anticonvulsants (phenytoin, barbiturates), NSAIDS, aspirin, antituberculous meds, allopurinol, etc. | |||
**Collagen Vascular Disorders: | |||
***RA, SLE, dermatomyositis, polyarteritis nodosa | |||
**Others: | |||
***Pregnancy, cold weather, sunlight, contact exposure, foods, malignancy, hormonal | |||
*Peak incidence in second and third decades of life | |||
*Despite multiple associations, thought to be triggered by HSV in most cases | |||
*Usually self-limited and resolves within 2-6 weeks; may recur | |||
*Wide spectrum of severity | |||
**Classified as Erythema multiforme minor or Erythema multiforme major | |||
==Clinical Features== | ==Clinical Features== | ||
Revision as of 02:28, 31 October 2014
Background
- Erythema Multiforme (EM) is an acute, self-limited skin condition precipitated by a variety of factors:
- Infections:
- Viral: HSV, hepatitis, influenza A
- Fungal: dermatophytosis, histoplasmosis, coccidioidomycosis
- Bacterial: streptococcus, tuberculosis
- Drugs:
- Antibiotics (penicillin, sulfonamides), anticonvulsants (phenytoin, barbiturates), NSAIDS, aspirin, antituberculous meds, allopurinol, etc.
- Collagen Vascular Disorders:
- RA, SLE, dermatomyositis, polyarteritis nodosa
- Others:
- Pregnancy, cold weather, sunlight, contact exposure, foods, malignancy, hormonal
- Infections:
- Peak incidence in second and third decades of life
- Despite multiple associations, thought to be triggered by HSV in most cases
- Usually self-limited and resolves within 2-6 weeks; may recur
- Wide spectrum of severity
- Classified as Erythema multiforme minor or Erythema multiforme major