Template:Acute cystitis antibiotics

Women, uncomplicated cystitis

• Nonpregnant, few prior UTI episodes, symptoms <7d, no flank pain or fever

1. Nitrofurantoin ER 100mg BID x 5d OR
2. TMP/SMX DS (160/800mg) 1 tab BID x 3d OR
3. Cephalexin 250mg QID x 5d OR
4. Ciprofloxacin 250mg BID x3d

Women, complicated cystitis/pyelo

• Risks for complicated UTI or symptoms of pyelo

1. Ciprofloxacin 500mg BID x10-14d OR
2. Cefpodoxime 200 mg BID x10-14d

Women, uncomplicated cystitis AND urethritis

1. Ceftriaxone 250mg IM x1 AND azithromycin 1gm PO x1 AND nitrofurantoin ER 100mg BID x5d OR
2. Levofloxacin 500mg QD x 14d (covers UTI pathogens, GC, and chlam)
   1. GC resistance to fluoroquinolones is increasing

Men, cystitis/pyelo

• Consider urethritis and prostatitis

1. Ciprofloxacin 500mg BID x10-14d OR
2. Cefpodoxime 200 mg BID x10-14d

Inpatient Options

• Ciprofloxacin 400mg IV q12hr OR
• Ceftriaxone 1gm IV QD OR
• Cefotaxime 1-2gm IV q8hr OR
• Gentamicin 3mg/kg/day divided q8hr +/- ampicillin 1–2 gm q4hr OR
• Piperacillin/Tazobactam 3.375 gm IV q6hr OR
• Cefepime 2gm IV q8hr OR
• Imipenem 500mg IV q8hr