Diltiazem: Difference between revisions
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==See Also== | ==See Also== | ||
*[[Antiarrhythmics]] | *[[Antiarrhythmics]] | ||
*[[ | *[[Calcium Channel Blocker Toxicity]] | ||
*[[Atrial Fibrillation with RVR]] | *[[Atrial Fibrillation with RVR]] | ||
[[Category:Drugs]] | [[Category:Drugs]] | ||
Revision as of 11:31, 23 October 2014
Adult Dosing
- Loading dose = 0.25mg/kg (max=20mg) IV bolus over 2min
- If ineffective after 15min: 0.35mg/g (max=25mg) over 2min
- If effective: Start infusion at 5-15mg/hr
Contraindications
- Wide-complex tachycardia due to bypass tract
Indications
- Conversion of PSVT to NSR
- Slow RVR in a-fib/flutter
Mechanism of Action
- Class IV - Inhibits Ca influx
- Slows AV nodal conduction
Adverse Drug Rxns
Bradycardia, CHF, AV block, BBB, hypotension
Kinetics
- Onset of action = 2-3min (IV)
- Duration of action = 1-3hr (IV)