Chondrosarcoma: Difference between revisions
Mtjordan91 (talk | contribs) |
Mtjordan91 (talk | contribs) |
||
| Line 40: | Line 40: | ||
==Management== | ==Management== | ||
*Surgery is the definitive treatment | |||
*Radiation and chemotherapy are ineffective as tumor is very slow growing | |||
==Disposition== | ==Disposition== | ||
Revision as of 22:28, 21 November 2019
Background
- Third most common primary bone malignancy after multiple myeloma and osteosarcoma
- Around ninety percent of chondrosarcomas are of low metastatic potential
- Osteochondromas and enchondromas can be precursors lesions
Pathophysiology
- Overproduction of chondroid matrix in the medullary cavity
Clinical Features
- Lesions commonly in the pelvis and central skeleton
- Occurs in patients over 40 years-old with a male predominance
- Often will present with local swelling and pain or a pathologic fracture
- Very slow growing tumors
Differential Diagnosis
Malignant
- Multiple myeloma
- Osteosarcoma
- Paget disease
- Ewing sarcoma
- Giant cell tumor
- Adamantinoma
- Chordoma
- Primary bone lymphoma
- Fibrosarcoma
- Myosarcoma
Benign
- Chrondroblastoma
- Enchondroma
- Langerhans cell histiocytosis of bone
- Osteoblastoma
- Osteochondroma
- Osteoid Osteoma
Evaluation
- Plain radiographs reveal punctate calcifications and cortical bone destruction
- CT or MRI to assess extent of bone involvement
- Bone biopsy for definitive diagnosis
Management
- Surgery is the definitive treatment
- Radiation and chemotherapy are ineffective as tumor is very slow growing