Rifaximin: Difference between revisions
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==Administration== | ==Administration== | ||
*Type: Antibiotic | *Type: [[Antibiotic]] | ||
*Dosage Forms: 200, 550 | *Dosage Forms: 200, 550 | ||
*Routes of Administration: Oral | *Routes of Administration: Oral | ||
| Line 6: | Line 6: | ||
==Adult Dosing== | ==Adult Dosing== | ||
*Traveler's diarrhea, E. coli-induced: | *Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days | ||
*Hepatic encephalopathy: | *Hepatic encephalopathy: 550mg PO bid | ||
*IBS, diarrhea-predominant: | *IBS, diarrhea-predominant: 550mg PO tid x14 days | ||
**May repeat dose up to 2x if recurrent | **May repeat dose up to 2x if recurrent disease | ||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
===For > 12 yrs old=== | ===For > 12 yrs old=== | ||
*Traveler's diarrhea, E. coli-induced: | *Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days | ||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*[[Lactation risk categories|Lactation risk]]: | *[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out | ||
===Renal Dosing=== | ===Renal Dosing=== | ||
*No adjustment | *No adjustment | ||
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<Epocrates, UpToDate> | <Epocrates, UpToDate> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] | ||
[[Category:ID]] [[Category:GI]] | |||
Latest revision as of 22:18, 23 September 2019
Administration
- Type: Antibiotic
- Dosage Forms: 200, 550
- Routes of Administration: Oral
- Common Trade Names: Xifaxan
Adult Dosing
- Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days
- Hepatic encephalopathy: 550mg PO bid
- IBS, diarrhea-predominant: 550mg PO tid x14 days
- May repeat dose up to 2x if recurrent disease
Pediatric Dosing
For > 12 yrs old
- Traveler's diarrhea, E. coli-induced: 200mg PO tid x3 days
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk cannot be ruled out
Renal Dosing
- No adjustment
Hepatic Dosing
- No adjustment
Contraindications
- Allergy to class/drug
- caution if hepatic impairment (Child-Pugh Class C)
- caution if recent antibiotic-associated colitis
Adverse Reactions
Serious
- superinfection
- C. difficile-assoc. diarrhea
- hypersensitivity reaction
- angioedema
- anaphylaxis
- exfoliative dermatitis
Common
- peripheral edema
- nausea
- dizziness
- fatigue
Comments
See Also
References
<Epocrates, UpToDate>