Middle East respiratory syndrome coronavirus: Difference between revisions
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==Diagnosis==
==Diagnosis==
#Criteria for MERS-CoV infection:
===CDC Case Definition<ref>http://www.cdc.gov/coronavirus/mers/case-def.html</ref>===
##Suspicion of pulmonary parenchymal disease (e.g., pneumonia or acute respiratory distress syndrome based on clinical or radiological evidence of consolidation); AND
A patient with ('''needs all three'''):
##History of travel within the past 14 days to the Arabian Peninsula or neighboring countries (Bahrain, Iraq, Iran, Israel, Jordan, Kuwait, Lebanon, Oman, Palestinian territories, Qatar, Saudi Arabia, Syria, the United Arab Emirates, and Yemen); AND
#Fever (≥38°C, 100.4°F) AND
##Illness is not already explained by any other infection or etiology, including all clinically indicated tests for community-acquired pneumonia.
#[[Pneumonia]] or acute respiratory distress syndrome (based on clinical or radiological evidence) AND
#In addition, the following persons may be considered for evaluation for MERS-CoV infection:
#One of the below:
##Persons who develop severe acute lower respiratory illness of known etiology within 10 days after traveling from the Arabian Peninsula or neighboring countries but who do not respond to appropriate therapy; OR
##history of travel from countries in or near the Arabian Peninsula^ within 14 days before symptom onset; OR
##Persons who develop severe acute lower respiratory illness who are close contacts of a symptomatic traveler who developed fever and acute respiratory illness within 10 days of traveling from the AP or neighboring countries.
##close contact^^ with a symptomatic traveler who developed [[fever]] and acute respiratory illness (not necessarily [[pneumonia]]) within 14 days after traveling from countries in or near the Arabian Peninsula^; OR
##is a member of a cluster of patients with severe acute respiratory illness (e.g. [[fever]] and [[pneumonia]] requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments.
 
^Countries considered in or near the Arabian Peninsula: Bahrain, Iraq, Iran, Israel, Jordan, Kuwait, Lebanon, Oman, Palestinian territories, Qatar, Saudi Arabia, Syria, the United Arab Emirates (UAE), and Yemen.
 
^^Close contact is defined as a) any person who provided care for the patient, including a healthcare worker or family member, or had similarly close physical contact; or b) any person who stayed at the same place (e.g. lived with, visited) as the patient while the patient was ill.


==Treatment==
==Treatment==

Revision as of 17:35, 5 May 2014

Background

  • New coronavirus was first described in September 2012, when it was reported to have caused fatal acute lower respiratory illness in a man in Saudi Arabia.
  • First US case reported in Indiana on May 1, 2014

Diagnosis

CDC Case Definition[1]

A patient with (needs all three):

  1. Fever (≥38°C, 100.4°F) AND
  2. Pneumonia or acute respiratory distress syndrome (based on clinical or radiological evidence) AND
  3. One of the below:
    1. history of travel from countries in or near the Arabian Peninsula^ within 14 days before symptom onset; OR
    2. close contact^^ with a symptomatic traveler who developed fever and acute respiratory illness (not necessarily pneumonia) within 14 days after traveling from countries in or near the Arabian Peninsula^; OR
    3. is a member of a cluster of patients with severe acute respiratory illness (e.g. fever and pneumonia requiring hospitalization) of unknown etiology in which MERS-CoV is being evaluated, in consultation with state and local health departments.

^Countries considered in or near the Arabian Peninsula: Bahrain, Iraq, Iran, Israel, Jordan, Kuwait, Lebanon, Oman, Palestinian territories, Qatar, Saudi Arabia, Syria, the United Arab Emirates (UAE), and Yemen.

^^Close contact is defined as a) any person who provided care for the patient, including a healthcare worker or family member, or had similarly close physical contact; or b) any person who stayed at the same place (e.g. lived with, visited) as the patient while the patient was ill.

Treatment

Immediately contact the Acute Communicable Disease Control Program (ACDC) at 213-240-7941, ask for the Administrator on Duty (AOD), if a patient meets criteria

See Also

The CDC guidance on MERS-CoV is available at http://www.cdc.gov/coronavirus/ncv/case-def.html

  1. ↑ http://www.cdc.gov/coronavirus/mers/case-def.html
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