Neisseria gonorrhoeae: Difference between revisions

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==Disposition==
==Disposition==


==Antibiotic Sensitivities<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Antibiotics'''
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''N. gonorrhoeae'''
|-
| Penicillins||Penicillin G||0
|-
| ||Penicillin V||0
|-
| Anti-Staphylocccal Penicillins||Methicillin||0
|-
| ||Nafcillin/Oxacillin||0
|-
| ||Cloxacillin/Diclox.||0
|-
| Amino-Penicillins||AMP/Amox||0
|-
| ||Amox/Clav||+
|-
| ||AMP-Sulb||+
|-
| Anti-Pseudomonal Penicillins||Ticarcillin||+
|-
| ||Ticar-Clav||+
|-
| ||Pip-Taxo||+
|-
| [[Carbapenems]]||Piperacillin||+
|-
| ||Doripenem||+
|-
| ||Ertapenem||+
|-
| ||Imipenem||+
|-
| ||Meropenem||+
|-
| ||[[Aztreonam]]||+
|-
| [[Fluroquinolones]]||[[Ciprofloxacin]]||+*
|-
| ||Ofloxacin||+*
|-
| ||Pefloxacin||+*
|-
| ||[[Levofloxacin]]||+*
|-
| ||Moxifloxacin||+*
|-
| ||Gemifloxacin||
|-
| ||Gatifloxacin||+*
|-
| 1st G [[Cephalosporin]]||Cefazolin||+
|-
| 2nd G.  [[Cephalosporin]]||[[Cefotetan]]||+/-
|-
| ||Cefoxitin||+/-
|-
| ||Cefuroxime||+/-
|-
| 3rd/4th G.  [[Cephalosporin]]||[[CefoTAXime]]||+/-
|-
| ||Cefizoxime||+/-
|-
| ||[[CefTRIAXone]]||+
|-
| ||Ceftobiprole||+
|-
| ||Ceftaroline||+
|-
| ||[[CefTAZidime]]||+/-
|-
| ||[[Cefepime]]||+
|-
| Oral 1st G.  [[Cephalosporin]]||Cefadroxil||0
|-
| ||[[Cephalexin]]||0
|-
| Oral 2nd G.  [[Cephalosporin]]||Cefaclor/Loracarbef||+/-
|-
| ||Cefproxil||+/-
|-
| ||Cefuroxime axetil||+/-
|-
| Oral 3rd G.  [[Cephalosporin]]||Cefixime||+
|-
| ||Ceftibuten||+/-
|-
| ||Cefpodox/Cefdinir/Cefditoren||+
|-
| [[Aminoglycosides]]||[[Gentamicin]]||0
|-
| ||Tobramycin||0
|-
| ||[[Amikacin]]||0
|-
| ||Chloramphenicol||+
|-
| ||[[Clindamycin]]||0
|-
| [[Macrolides]]||Erythromycin||+/-
|-
| ||[[Azithromycin]]||+/-
|-
| ||Clarithromycin||+/-
|-
| Ketolide||Telithromycin||+
|-
| Tetracyclines||[[Doxycycline]]||+/-
|-
| ||Minocycline||+/-
|-
| Glycylcycline||Tigecycline||+
|-
| Glyco/Lipoclycopeptides||[[Vancomycin]]||0
|-
| ||Teicoplanin||0
|-
| ||Telavancin||0
|-
| ||Fusidic Acid||+
|-
| ||Trimethoprim||0
|-
| ||[[TMP-SMX]]||+/-
|-
| Urinary Agents||[[Nitrofurantoin]]||+
|-
| ||Fosfomycin||+
|-
| Other||[[Rifampin]]||+
|-
| ||[[Metronidazole]]||0
|-
| ||Quinupristin dalfoppristin||+
|-
| ||Linezolid||
|-
| ||[[Daptomycin]]||0
|-
| ||Colistimethate||0
|}
===Key===
{{Template:Antibacterial Spectra Key}}
==Table Overview==
{{Clinically Relevant Bacteria}}
==See Also==
==See Also==
*[[STDs]]
*[[STDs]]
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==Sources==
==Sources==
<references/>
<references/>
{{Clinically Relevant Bacteria}}


[[Category:ID]]
[[Category:ID]]
[[Category:GU]]
[[Category:GU]]

Revision as of 07:57, 4 March 2014

Background

Clinical Features

Differential Diagnosis

Workup

Management

Disposition

Antibiotic Sensitivities[1]

Antibiotics ' N. gonorrhoeae
Penicillins Penicillin G 0
Penicillin V 0
Anti-Staphylocccal Penicillins Methicillin 0
Nafcillin/Oxacillin 0
Cloxacillin/Diclox. 0
Amino-Penicillins AMP/Amox 0
Amox/Clav +
AMP-Sulb +
Anti-Pseudomonal Penicillins Ticarcillin +
Ticar-Clav +
Pip-Taxo +
Carbapenems Piperacillin +
Doripenem +
Ertapenem +
Imipenem +
Meropenem +
Aztreonam +
Fluroquinolones Ciprofloxacin +*
Ofloxacin +*
Pefloxacin +*
Levofloxacin +*
Moxifloxacin +*
Gemifloxacin
Gatifloxacin +*
1st G Cephalosporin Cefazolin +
2nd G. Cephalosporin Cefotetan +/-
Cefoxitin +/-
Cefuroxime +/-
3rd/4th G. Cephalosporin CefoTAXime +/-
Cefizoxime +/-
CefTRIAXone +
Ceftobiprole +
Ceftaroline +
CefTAZidime +/-
Cefepime +
Oral 1st G. Cephalosporin Cefadroxil 0
Cephalexin 0
Oral 2nd G. Cephalosporin Cefaclor/Loracarbef +/-
Cefproxil +/-
Cefuroxime axetil +/-
Oral 3rd G. Cephalosporin Cefixime +
Ceftibuten +/-
Cefpodox/Cefdinir/Cefditoren +
Aminoglycosides Gentamicin 0
Tobramycin 0
Amikacin 0
Chloramphenicol +
Clindamycin 0
Macrolides Erythromycin +/-
Azithromycin +/-
Clarithromycin +/-
Ketolide Telithromycin +
Tetracyclines Doxycycline +/-
Minocycline +/-
Glycylcycline Tigecycline +
Glyco/Lipoclycopeptides Vancomycin 0
Teicoplanin 0
Telavancin 0
Fusidic Acid +
Trimethoprim 0
TMP-SMX +/-
Urinary Agents Nitrofurantoin +
Fosfomycin +
Other Rifampin +
Metronidazole 0
Quinupristin dalfoppristin +
Linezolid
Daptomycin 0
Colistimethate 0

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

Gram Positives
Cocci
Clusters
Pairs/Chains
Other
Rods
Gram Negatives
Cocci
Rods
Lactose Fermenters
Lactose Non-Fermenters
Other
Rods/Cocci
Anaerobes

See Also

Sources

  1. ↑ Sanford Guide to Antimicrobial Therapy 2010
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