Cetacaine: Difference between revisions
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==General Information== | ==General Information== | ||
[[File:cetylite-cetacaine-spray-20g-0220.jpg|thumb|]] | |||
Cetacaine is the brand name of a commonly available topical mucosal anesthetic, which is a combination of 14% benzocaine, 2% tetracaine hydrochloride, and 2% butamben. This is slightly different from another readily available topical anesthetic, HurriCaine spray, which is composed of 20% benzocaine. | Cetacaine is the brand name of a commonly available topical mucosal anesthetic, which is a combination of 14% benzocaine, 2% tetracaine hydrochloride, and 2% butamben. This is slightly different from another readily available topical anesthetic, HurriCaine spray, which is composed of 20% benzocaine. | ||
==Administration== | ==Administration== | ||
*Type: Topical anesthetic | *Type: Topical anesthetic | ||
Revision as of 22:09, 18 March 2018
General Information
Cetacaine is the brand name of a commonly available topical mucosal anesthetic, which is a combination of 14% benzocaine, 2% tetracaine hydrochloride, and 2% butamben. This is slightly different from another readily available topical anesthetic, HurriCaine spray, which is composed of 20% benzocaine.
Administration
- Type: Topical anesthetic
- Dosage Forms: Spray, gel, solution
- Routes of Administration: Mucosal
- Common Trade Names: Cetacaine; Exactacain
Adult Dosing
Spray form
- Apply maximum 2 second spray
Gel form
- Apply a maximum of 1 inch of gel
Solution form
- Apply a maximum of 0.4cc
Pediatric Dosing
No pediatric dosing established
Special Populations
- Pregnancy Rating: Category C
- Lactation risk: Safety unknown
Renal Dosing
- Adult: N/A
- Pediatric: N/A
Hepatic Dosing
- Adult: N/A
- Pediatric: N/A
Contraindications
- Allergy to class/drug
- Cholinesterase deficincies
- Use caution in G6PD and Hgb-M patients
- Avoid using on significantly inflamed or macerated tissue
Adverse Reactions
Serious
Common
- Contact dermatitis
- Xeroderma
Pharmacology
- Half-life: Unknown
- Metabolism: Plasma cholinesterase, liver
- Excretion: Urine (minimal systemic absorption)
Mechanism of Action
- Ester anesthetic, inhibits Na ion channels and nerve impulse/conduction
Comments
See Also
References
Micromedex
US FDA benzocaine warning. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm250264.htm