Blood products: Difference between revisions
(Created page with "==PRBCs== Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0 Indications (by Hb): Normal (rarely if >10; almost always if <6) Critically ill, otherwise h...") |
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==PRBCs== | ==PRBCs== | ||
#Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0 | |||
#Indications (by Hb): | |||
Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0 | #Normal (rarely if >10; almost always if <6) | ||
#Critically ill, otherwise healthy (keep > 7-9) | |||
Indications (by Hb): | #Ischemic heart dz/critically ill age >65 (keep >10) | ||
Normal (rarely if >10; almost always if <6) | |||
Critically ill, otherwise healthy (keep > 7-9) | |||
Ischemic heart dz/critically ill age >65 (keep >10) | |||
==FFP== | ==FFP== | ||
#Usual Dose: 10-20 ml/kg (average adult = 3-6 units) | |||
#2 U of FFP (450 mL) should correct most early coagulopathies | |||
Usual Dose: 10-20 ml/kg (average adult = 3-6 units) | #An INR of 2.0 correlates w/ PT 1.5 times nl | ||
Indications: | Indications: | ||
# Active bleeding AND PT/PTT >1.5 times nl (INR >2.0) | |||
# INR >20.0 | |||
# Massive PRBC transfusion (>9 U) | |||
# DIC not corrected by cryo. | |||
# Coumadin overdose AND life threat bleed/invasive procedure | |||
==Platelets== | ==Platelets== | ||
#Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000. | |||
#1 U (25-50 mL = "6-pack") --> incr plat 5-10,000 (adult) or 20,000 (20 kg child) | |||
Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000. | #Indications: See "HEME: Thrombocytopenia" | ||
==Risks== | ==Risks== | ||
#Hep B ~1:100,000 | |||
#Hep C ~1:1 million | |||
Hep B ~1:100,000 | #HIV 1:2 million | ||
Hep C ~1:1 million | |||
HIV 1:2 million | |||
==Source == | ==Source == | ||
2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen) | 2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen) | ||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Revision as of 13:29, 15 March 2011
PRBCs
- Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0
- Indications (by Hb):
- Normal (rarely if >10; almost always if <6)
- Critically ill, otherwise healthy (keep > 7-9)
- Ischemic heart dz/critically ill age >65 (keep >10)
FFP
- Usual Dose: 10-20 ml/kg (average adult = 3-6 units)
- 2 U of FFP (450 mL) should correct most early coagulopathies
- An INR of 2.0 correlates w/ PT 1.5 times nl
Indications:
- Active bleeding AND PT/PTT >1.5 times nl (INR >2.0)
- INR >20.0
- Massive PRBC transfusion (>9 U)
- DIC not corrected by cryo.
- Coumadin overdose AND life threat bleed/invasive procedure
Platelets
- Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000.
- 1 U (25-50 mL = "6-pack") --> incr plat 5-10,000 (adult) or 20,000 (20 kg child)
- Indications: See "HEME: Thrombocytopenia"
Risks
- Hep B ~1:100,000
- Hep C ~1:1 million
- HIV 1:2 million
Source
2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen)