Factor VIII inhibitor: Difference between revisions
(Created page with "==Background== #(PTT does not correct after mixing) ==Management with Bleeding== #high dose Factor VII, prothrombin, or recombinant factor VIIa ==See Also== *Coagulopathy ...") |
(Text replacement - "==References== " to "==References== <references/> ") |
||
| (4 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
==Background== | ==Background== | ||
==Management | ==Clinical Features== | ||
==Differential Diagnosis== | |||
{{Increased bleeding DDX}} | |||
==Evaluation== | |||
*PTT does not correct after mixing | |||
==Management== | |||
*Bleeding | |||
**Give high dose Factor VII, prothrombin, or recombinant factor VIIa | |||
==Disposition== | |||
==See Also== | ==See Also== | ||
*[[Coagulopathy (Main)]] | *[[Coagulopathy (Main)]] | ||
== | ==References== | ||
<references/> | |||
[[Category:Heme/Onc]] | [[Category:Heme/Onc]] | ||
Latest revision as of 01:13, 24 July 2017
Background
Clinical Features
Differential Diagnosis
Coagulopathy
Platelet Related
- Too few
- Nonfunctional
Factor Related
- Acquired (Drug Related)
- Warfarin (Coumadin)
- Unfractionated heparin
- Low molecular weight heparin (i.e. enoxaparin (Lovenox), dalteparin)
- Factor Xa Inhibitors (e.g. rivaroxaban, apixaban, fondaparinux, edoxaban)
- Direct thrombin inhibitors (e.g. dabigatran, argatroban, bivalirudin)
- Illness induced
- Genetic
Evaluation
- PTT does not correct after mixing
Management
- Bleeding
- Give high dose Factor VII, prothrombin, or recombinant factor VIIa