Ethylene dibromide toxicity: Difference between revisions
m (Rossdonaldson1 moved page Ethylene Dibromide to Ethylene dibromide toxicity) |
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*Volatile liquid used in leaded gasoline and pesticides | *Volatile liquid used in leaded gasoline and pesticides | ||
==Mechanism of Toxicity== | ===Mechanism of Toxicity=== | ||
*Irritant, with potential to cause chemical burns | *Irritant, with potential to cause chemical burns | ||
*Respiratory tract irritation if inhaled | *Respiratory tract irritation if inhaled | ||
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==Clinical Features== | ==Clinical Features== | ||
*Pulmonary edema | *[[Pulmonary edema]] | ||
*Respiratory tract irritation | *Respiratory tract irritation | ||
*Eye irritation | *Eye irritation | ||
*Local swelling, inflammation with skin exposure | *Local swelling, inflammation with skin exposure | ||
*Diarrhea | *[[Diarrhea]] | ||
*Vomiting | *[[Vomiting]] | ||
*Coma | *[[Coma]] | ||
*Seizures | *[[Seizures]] | ||
*Rhabdomyolysis | *[[Rhabdomyolysis]] | ||
*Metabolic acidosis | *[[Metabolic acidosis]] | ||
==Differential Diagnosis== | |||
==Evaluation== | ==Evaluation== | ||
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*Treat wheezing, obstruction, pulmonary edema | *Treat wheezing, obstruction, pulmonary edema | ||
*No role for hemodialysis | *No role for hemodialysis | ||
==Disposition== | |||
==References== | ==References== | ||
Revision as of 05:13, 17 May 2017
Background
- Volatile liquid used in leaded gasoline and pesticides
Mechanism of Toxicity
- Irritant, with potential to cause chemical burns
- Respiratory tract irritation if inhaled
- Metabolites irreversibly bind to DNA and enzymes
Clinical Features
- Pulmonary edema
- Respiratory tract irritation
- Eye irritation
- Local swelling, inflammation with skin exposure
- Diarrhea
- Vomiting
- Coma
- Seizures
- Rhabdomyolysis
- Metabolic acidosis
Differential Diagnosis
Evaluation
- Based on clinical history
- Specific levels are not useful in the ED
Management
- Decontamination measures
- Administer activated charcoal
- Treat wheezing, obstruction, pulmonary edema
- No role for hemodialysis
Disposition
References
- Olson, K. Poisoning and Drug Overdose, 1999.