Vitamin K deficiency: Difference between revisions

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#Cholestasis: since it is fat soluble and needs bile salts to be absorbed
#Cholestasis: since it is fat soluble and needs bile salts to be absorbed


=Treatment for Deficiency)=
=Treatment for Deficiency=
#Fresh Frozen Plasma: 1ml contains 1U of each clotting factor
#Fresh Frozen Plasma: 1ml contains 1U of each clotting factor
#Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off
#Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off

Revision as of 22:59, 24 August 2013

Background

  1. Cofactor for vitamin K-dependent clotting factors II, VII, IX, X
    1. Used by liver
    2. Fat soluble

Differential Diagnosis of Deficiency

  1. Nutritional deficiency
  2. Malabsorption
  3. Cholestasis: since it is fat soluble and needs bile salts to be absorbed

Treatment for Deficiency

  1. Fresh Frozen Plasma: 1ml contains 1U of each clotting factor
  2. Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off

See Also