Vitamin K deficiency: Difference between revisions
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#Cholestasis: since it is fat soluble and needs bile salts to be absorbed | #Cholestasis: since it is fat soluble and needs bile salts to be absorbed | ||
=Treatment for Deficiency | =Treatment for Deficiency= | ||
#Fresh Frozen Plasma: 1ml contains 1U of each clotting factor | #Fresh Frozen Plasma: 1ml contains 1U of each clotting factor | ||
#Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off | #Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off | ||
Revision as of 22:59, 24 August 2013
Background
- Cofactor for vitamin K-dependent clotting factors II, VII, IX, X
- Used by liver
- Fat soluble
Differential Diagnosis of Deficiency
- Nutritional deficiency
- Malabsorption
- Cholestasis: since it is fat soluble and needs bile salts to be absorbed
Treatment for Deficiency
- Fresh Frozen Plasma: 1ml contains 1U of each clotting factor
- Consider Vitamin K oral or IV (subcutaneous not recommended): will take up to 24 hours to work and up to 2 weeks to wear off
