Loop diuretic: Revision history

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28 January 2026

  • curprev 00:3600:36, 28 January 2026Ostermayer talk contribs 1,810 bytes +1,810 Created page with "== Background == * Mechanism: Inhibits Na-K-2Cl carrier in the '''thick ascending Loop of Henle'''^1^ * Potency: Highest among diuretic classes * '''Adverse Effects''' ** Hypokalemia (most common) ** Hypomagnesemia, hyponatremia, hypocalcemia ** Ototoxicity (associated with rapid IV push) ** Pre-renal AKI (due to over-diuresis) * '''Sulfa Allergy:''' Most are sulfonamide derivatives; cross-reactivity is rare but possible == Key Agents == * '''F..."