Warfarin-induced skin necrosis - Revision history

Rossdonaldson1: /* Clinical Features */

2020-09-08T20:56:03Z

Clinical Features

← Older revision		Revision as of 20:56, 8 September 2020
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	==Clinical Features==		==Clinical Features==
			[[File:Right leg affected by warfarin necrosis.png\|thumb\|Right leg affected by warfarin necrosis.]]
	[[File:WarfarinNecrosis.png\|thumb]]		[[File:WarfarinNecrosis.png\|thumb]]
	*Painful, red [[rash\|lesions]] over extremities, trunk, penis		*Painful, red [[rash\|lesions]] over extremities, trunk, penis

Rossdonaldson1 at 20:54, 8 September 2020

2020-09-08T20:54:55Z

← Older revision		Revision as of 20:54, 8 September 2020
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	~~[[File:WarfarinNecrosis.png\|thumb]]~~
	==Background==		==Background==
	*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially→ hypercoagulability		*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially→ hypercoagulability
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	==Clinical Features==		==Clinical Features==
			[[File:WarfarinNecrosis.png\|thumb]]
	*Painful, red [[rash\|lesions]] over extremities, trunk, penis		*Painful, red [[rash\|lesions]] over extremities, trunk, penis
	*Start with erythematous macule→ edema→ central purpuric zones → necrosis		*Start with erythematous macule→ edema→ central purpuric zones → necrosis

ClaireLewis at 19:29, 1 October 2019

2019-10-01T19:29:49Z

← Older revision		Revision as of 19:29, 1 October 2019
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	*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially→ hypercoagulability		*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially→ hypercoagulability
	*Onset usually in first week of starting [[warfarin]]		*Onset usually in first week of starting [[warfarin]]

	==Clinical Features==		==Clinical Features==
	*Painful, red lesions over extremities, trunk, penis		*Painful, red [[rash\|lesions]] over extremities, trunk, penis
	*Start with erythematous macule→ edema→ central purpuric zones → necrosis		*Start with erythematous macule→ edema→ central purpuric zones → necrosis

	==Differential Diagnosis==		==Differential Diagnosis==
			{{Necrotizing Rashes DDX}}

	==Evaluation==		==Evaluation==
			*Clinical diagnosis

	==Management==		==Management==
	*Stop warfarin		*Stop warfarin
	*[[Low molecular weight heparin]] or unfractionated [[heparin]]		*[[Low molecular weight heparin]] or unfractionated [[heparin]]

	==Disposition==		==Disposition==

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	[[Category:Heme/Onc]]		[[Category:Heme/Onc]]
			[[Category:Dermatology]]

Mholtz: Text replacement - "-->" to "→"

2017-02-08T19:36:36Z

Text replacement - "-->" to "→"

← Older revision		Revision as of 19:36, 8 February 2017
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	[[File:WarfarinNecrosis.png\|thumb]]		[[File:WarfarinNecrosis.png\|thumb]]
	==Background==		==Background==
	*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency ~~initially-->~~ hypercoagulability		*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially→ hypercoagulability
	*Onset usually in first week of starting [[warfarin]]		*Onset usually in first week of starting [[warfarin]]
	==Clinical Features==		==Clinical Features==
	*Painful, red lesions over extremities, trunk, penis		*Painful, red lesions over extremities, trunk, penis
	*Start with erythematous ~~macule--> edema-->~~ central purpuric zones ~~-->~~ necrosis		*Start with erythematous macule→ edema→ central purpuric zones → necrosis
	==Differential Diagnosis==		==Differential Diagnosis==

ClaireLewis: Created page with "thumb ==Background== *Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially--> hyperco..."

2016-09-22T17:32:39Z

Created page with "thumb ==Background== *Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially--> hyperco..."

New page

[[File:WarfarinNecrosis.png|thumb]]
==Background==
*Differing half-lives of Vitamin-K dependent coagulation factors leads to relative protein C deficiency initially--> hypercoagulability
*Onset usually in first week of starting [[warfarin]]
==Clinical Features==
*Painful, red lesions over extremities, trunk, penis
*Start with erythematous macule--> edema--> central purpuric zones --> necrosis
==Differential Diagnosis==

==Evaluation==

==Management==
*Stop warfarin
*[[Low molecular weight heparin]] or unfractionated [[heparin]]
==Disposition==

==See Also==

==External Links==

==References==
<references/>

[[Category:Heme/Onc]]