Theophylline - Revision history

Mholtz at 06:38, 13 July 2017

2017-07-13T06:38:03Z

← Older revision		Revision as of 06:38, 13 July 2017
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	==References==		==References==
			<references/>

	~~<references/>~~
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

ClaireLewis at 00:34, 14 November 2016

2016-11-14T00:34:26Z

← Older revision		Revision as of 00:34, 14 November 2016
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	==General==		==General==
	*Type: a		*Type: Bronchodilator
	*Dosage Forms: ~~100,200,300,400,450,600 ER; 80/15 mL; IV~~		*Dosage Forms: Oral
	*Common Trade Names: Elixophyllin, Theo-24, Uniphyl		*Common Trade Names: Elixophyllin, Theo-24, Uniphyl

	==Adult Dosing==		==Adult Dosing==
			*300-600mg PO q6-8h (immediate-release) or q12h (ER)
			*IV theophylline no longer recommended for use inpatient or in the ED due to lack of added benefit over other treatments and high risk of adverse events<ref>National Heart, Lung, and Blood Institute: Expert panel report 3: guidelines for the diagnosis and management of asthma. National Heart, Lung, and Blood Institute. Bethesda, MD. 2007. http://www.nhlbi.nih.gov/health-pro/guidelines/current/asthma-guidelines</ref><ref>Kallstrom TJ. Evidence-based asthma management. Respir Care. 2004;49(7):783-92.</ref>

	==Pediatric Dosing==		==Pediatric Dosing==
			*Apnea in neonate: 4 mg/kg IV load, then 2 mg/kg IV q12h
			*Pediatric theophylline doses for asthma are very complicated, and with the narrow therapeutic window, probably not even worth trying it!

	==Special Populations==		==Special Populations==
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	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Known allergy to corn or corn products (IV form)
	*caution if PUD, active		*caution if PUD, active
	*caution if seizure disorder		*caution if seizure disorder
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	*seizures		*seizures
	*arrhythmias		*arrhythmias
	*hypotension		*hypotension, shock
	*shock
	*exfoliative dermatitis		*exfoliative dermatitis

	===Common===		===Common===
	*nausea		*nausea/vomiting, diarrhea
	*vomiting
	*headache		*headache
	*insomnia		*insomnia, irritability, restlessness, tremor
	*diarrhea
	*irritability
	*restlessness
	*tremor
	*diuresis, transient		*diuresis, transient

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	==See Also==		==See Also==
			*[[Theophylline toxicity]]
			*[[Bronchodilators]]

	==References==		==References==

Rossdonaldson1: /* Adverse Reactions */

2016-09-20T22:17:31Z

Adverse Reactions

← Older revision		Revision as of 22:17, 20 September 2016
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	==Adverse Reactions==		==Adverse Reactions==
			''See [[theophylline toxicity]] for overdose information''
	===Serious===		===Serious===
	*seizures		*seizures

ClaireLewis: /* Special Populations */

2016-07-15T20:45:23Z

Special Populations

← Older revision		Revision as of 20:45, 15 July 2016
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	*Renal Dosing		*Renal Dosing
	**Adult: no adjustment		**Adult: no adjustment
	**Pediatric: <3 mo: ~~decr.~~ dose amount not defined; >3 mo: no adjustment		**Pediatric: <3 mo: decrease dose amount not defined; >3 mo: no adjustment
	*Hepatic Dosing		*Hepatic Dosing
	**Adult: ~~decr.~~ dose amount not defined		**Adult: decrease dose amount not defined
	**Pediatric: ~~decr.~~ dose amount not defined		**Pediatric: decrease dose amount not defined

	==Contraindications==		==Contraindications==

Neil.m.young: Text replacement - " w/ " to " with "

2016-07-12T21:57:07Z

Text replacement - " w/ " to " with "

← Older revision		Revision as of 21:57, 12 July 2016
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	*caution if hypothyroidism		*caution if hypothyroidism
	*caution if febrile		*caution if febrile
	*caution if sepsis w/ multi-organ failure		*caution if sepsis with multi-organ failure
	*caution if shock		*caution if shock
	*caution if smoking habit changes		*caution if smoking habit changes

Neil.m.young: Text replacement - "==Sources==" to "==References=="

2016-06-26T20:02:14Z

Text replacement - "==Sources==" to "==References=="

← Older revision		Revision as of 20:02, 26 June 2016
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	==See Also==		==See Also==

	==~~Sources~~==		==References==

	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Ostermayer: Text replacement - " pts" to " patients"

2016-06-21T16:49:29Z

Text replacement - " pts" to " patients"

← Older revision		Revision as of 16:49, 21 June 2016
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	*caution if smoking habit changes		*caution if smoking habit changes
	*caution if neonates or infants		*caution if neonates or infants
	*caution in elderly ~~pts~~		*caution in elderly patients

	==Adverse Reactions==		==Adverse Reactions==

Ostermayer: Text replacement - "Category:Drugs" to "Category:Pharmacology"

2016-03-22T15:53:07Z

Text replacement - "Category:Drugs" to "Category:Pharmacology"

← Older revision		Revision as of 15:53, 22 March 2016
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	<references/>		<references/>
	[[Category:~~Drugs~~]]		[[Category:Pharmacology]]

Tashfern: /* General */

2015-06-30T22:26:44Z

General

← Older revision		Revision as of 22:26, 30 June 2015
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	==General==		==General==
	*Type:		*Type: a
	*Dosage Forms:		*Dosage Forms: 100,200,300,400,450,600 ER; 80/15 mL; IV
	*Common Trade Names:		*Common Trade Names: Elixophyllin, Theo-24, Uniphyl

	==Adult Dosing==		==Adult Dosing==

Tashfern: /* Contraindications */

2015-06-30T22:24:39Z

Contraindications

@@ Line 20: / Line 20: @@
 ==Contraindications==
 *Allergy to class/drug
 ==Adverse Reactions==