Thallium toxicity - Revision history

Mholtz at 09:22, 23 October 2017

2017-10-23T09:22:16Z

← Older revision		Revision as of 09:22, 23 October 2017
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	==Management==		==Management==
	*Prussian blue is mainstay of therapy ~~in Europe~~		*Prussian blue is mainstay of therapy
	**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling		**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling
	*[[Activated charcoal]] binds thallium in vitro		*[[Activated charcoal]] binds thallium in vitro
	*[[Ipecac]] can be given in the prehospital setting if given within first few minutes of exposure

	==Disposition==		==Disposition==


	==See Also==		==See Also==
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	==References==		==References==
	<references/>		<references/>
	[[Category:Toxicology~~]] [[Category:Environmental~~]]
			[[Category:Toxicology]]

2016-12-10T06:55:37Z

Clinical Features

← Older revision		Revision as of 06:55, 10 December 2016
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	==Clinical Features==		==Clinical Features==
	*Acute:		===Acute===
	**12 hours: Abdominal pain, nausea, vomiting, diarrhea, shock		*12 hours: [[Abdominal pain]], [[nausea]], [[vomiting]], [[diarrhea]], [[shock]]
	**2-3 days: delirium, respiratory failure, seizures, death		*2-3 days: [[delirium]], [[respiratory failure]], [[seizures]], [[death]]
	*Chronic:
	**2-4 weeks: peripheral neuropathy, chorea, stomatitis, hair loss		===Chronic===
			*2-4 weeks: [[peripheral neuropathy]], [[chorea]], [[stomatitis]], hair loss

	==Differential Diagnosis==		==Differential Diagnosis==

2016-12-10T06:54:33Z

Management

← Older revision		Revision as of 06:54, 10 December 2016
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	**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling		**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling
	*[[Activated charcoal]] binds thallium in vitro		*[[Activated charcoal]] binds thallium in vitro
	*[[~~Ipeca~~]]c can be given in the prehospital setting if given within first few minutes of exposure		*[[Ipecac]] can be given in the prehospital setting if given within first few minutes of exposure

	==Disposition==		==Disposition==

2016-12-10T06:54:18Z

Management

← Older revision		Revision as of 06:54, 10 December 2016
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	*Prussian blue is mainstay of therapy in Europe		*Prussian blue is mainstay of therapy in Europe
	**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling		**Crystal lattice structure binds thallium ions, preventing enterohepatic recycling
	*Activated charcoal binds thallium in vitro		*[[Activated charcoal]] binds thallium in vitro
	*~~Ipecac~~ can be given in the prehospital setting if given within first few minutes of exposure		*[[Ipeca]]c can be given in the prehospital setting if given within first few minutes of exposure

	==Disposition==		==Disposition==

2016-12-10T06:53:51Z

← Older revision		Revision as of 06:53, 10 December 2016
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	*Quickly oxidizes with exposure to air		*Quickly oxidizes with exposure to air

	==Mechanism of Toxicity==		===Mechanism of Toxicity===
	*Unknown: seems to affect various enzyme systems		*Unknown: seems to affect various enzyme systems
	*Lethal dose 12-15 mg/kg		*Lethal dose 12-15 mg/kg
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	*Chronic:		*Chronic:
	**2-4 weeks: peripheral neuropathy, chorea, stomatitis, hair loss		**2-4 weeks: peripheral neuropathy, chorea, stomatitis, hair loss

			==Differential Diagnosis==
			{{Heavy metals list}}

	==Evaluation==		==Evaluation==
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	*Activated charcoal binds thallium in vitro		*Activated charcoal binds thallium in vitro
	*Ipecac can be given in the prehospital setting if given within first few minutes of exposure		*Ipecac can be given in the prehospital setting if given within first few minutes of exposure

			==Disposition==

			==See Also==
			*[[Heavy metal toxicity]]

	==References==		==References==
	<references/>		<references/>
	[[Category:Toxicology]] [[Category:Environmental]]		[[Category:Toxicology]] [[Category:Environmental]]

2016-12-10T06:52:57Z

Rossdonaldson1 moved page Thallium to Thallium toxicity

← Older revision	Revision as of 06:52, 10 December 2016
(No difference)

2016-12-09T21:55:09Z

← Older revision		Revision as of 21:55, 9 December 2016
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	==References==		==References==
	<references/>		<references/>
	[[Category:Toxicology]]		[[Category:Toxicology]] [[Category:Environmental]]

2016-12-09T21:54:53Z

2016-12-09T21:54:26Z

← Older revision		Revision as of 21:54, 9 December 2016
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	==References==		==References==
	~~Olson, K. Poisoning and Drug Overdose Clinical Manual. 2004~~		<references/>

2016-12-09T04:30:26Z

← Older revision		Revision as of 04:30, 9 December 2016
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	*Quickly oxidizes with exposure to air		*Quickly oxidizes with exposure to air

	===Mechanism of Toxicity===		==Mechanism of Toxicity==
	*Unknown: seems to affect various enzyme systems		*Unknown: seems to affect various enzyme systems
	*Lethal dose 12-15 mg/kg		*Lethal dose 12-15 mg/kg