https://wikem.org/w/index.php?action=history&feed=atom&title=Template%3ARenal_tubular_disorders_DDX 2026-04-20T20:06:47Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Template:Renal_tubular_disorders_DDX&diff=386186&oldid=prev 2026-03-19T11:26:36Z

<p>Created Renal tubular disorders DDX template</p> <p><b>New page</b></p><div>===Renal tubular disorders===<br /> *Salt-wasting tubulopathies<br /> **[[Gitelman syndrome]] — distal convoluted tubule (NCC defect); hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis<br /> **[[Bartter syndrome]] — thick ascending limb (NKCC2/ROMK/ClC-Kb defect); hypokalemia, hypercalciuria, metabolic alkalosis<br /> **[[Liddle syndrome]] — collecting duct (ENaC gain-of-function); hypokalemia, hypertension, metabolic alkalosis<br /> *Renal tubular acidosis<br /> **[[Renal tubular acidosis]] type I (distal) — hypokalemia, metabolic acidosis, nephrocalcinosis<br /> **[[Renal tubular acidosis]] type II (proximal) — hypokalemia, metabolic acidosis, Fanconi syndrome<br /> **[[Renal tubular acidosis]] type IV — hyperkalemia, metabolic acidosis, hypoaldosteronism<br /> *Inherited disorders of tubular transport<br /> **[[Cystinuria]] — proximal tubule amino acid transport defect; recurrent cystine stones<br /> **Fanconi syndrome — proximal tubule generalized dysfunction; glucosuria, aminoaciduria, phosphaturia<br /> **[[Nephrogenic diabetes insipidus]] — collecting duct (aquaporin/V2R defect); polyuria, hypernatremia<br /> **Dent disease — proximal tubule (ClC-5 defect); low molecular weight proteinuria, nephrocalcinosis<br /> *Acquired tubulopathies<br /> **Diuretic use/abuse (thiazide mimics Gitelman; loop mimics Bartter)<br /> **[[Aminoglycosides]] nephrotoxicity<br /> **[[Cisplatin]] nephrotoxicity<br /> **[[Amphotericin B]] nephrotoxicity<br /> **[[Lithium]]-induced nephrogenic DI</div>

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